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Skip to Search Results- 33Mass-spectrometry
- 29Chemistry
- 23Organic compounds. Synthesis.
- 22Catalysis
- 22Metabolomics
- 21Capillary electrophoresis.
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Fall 2011
The pradimicins are natural products that are both structurally intriguing to a synthetic chemist and possess biological activity as antifungal and antiviral agents. Our interest towards designing a synthetic route for these compounds and various analogues was sparked by the potential to produce...
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Fall 2009
In an attempt to expand the scope of titanacyclobutenes, malonate-derived α,ω-alkylpropargyl dibromides and α,ω-bis(bromopropargyl) malonates were prepared and examined for their reactivity with titanocene reagents. Unfortunately, all of the α,ω-alkylpropargyl dibromomalonates failed, presumably...
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Spring 2014
As one of the most commonly applied semiconductors, nanostructured silicon has received considerable attention over the past several decades due to its suitable band gap for light harvesting (1.2 eV for bulk crystal and up to 1.9 eV for nanocrystals), unique tunable photoluminescence (PL) and...
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Development and Applications of Quantitative Mass Spectrometric Methods for Proteome and Protein Analysis
DownloadSpring 2013
Quantitative proteomics has been increasingly recognized as a key research topic in proteomics research, as it enumerates changes of proteins’ expression level in a bio-system. Quantitative proteomics provides an important way to discover biomarkers for disease diagnosis and prognosis, and also...
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A general route to 1,3'-bipyrroles, conversion of cyclohexenone-type systems into phenols and synthetic studies on Coleophomone B
DownloadFall 2016
Chapter 1 describes a general route for making 1,3'-bipyrroles. This work involves intermolecular conjugate displacement using a special Michael acceptor developed in this laboratory. This method is general and enables the construction of highly substituted 1,3'-bipyrroles. The route was first...
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Synthesis of the repeating unit of Streptococcus pneumoniae (Sp1) zwitterionic polysaccharide
DownloadFall 2010
According to the traditional paradigm, carbohydrates are considered to be poorly immunogenic, T-cell independent antigens. Pure polysaccharides induce specific IgM responses, with minimal class switch to IgG. However, a series of recent investigations has found that a class of zwitterionic...
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Development and Characterization of New Stationary Phases for Hydrophilic Interaction Liquid Chromatography
DownloadSpring 2014
Ibrahim, Mohammed Elsayed Abdelatif
Hydrophilic interaction liquid chromatography (HILIC) has gained high popularity among separation scientists in the last two decades due to its ability to retain polar analytes. Many new HILIC stationary phases with different selectivities have appeared in the recent literature. Such developments...
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Fall 2019
The processes of assembly and disassembly of colloids has rapidly grown in interest over the decades. Assembly and disassembly are able to respond to the changes in conditions, which makes them important in sensing and stimuli-reponsive processes. There are two applications based on assembly and...