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Skip to Search Results- 2Chun, Justin
- 1Aktary, Zackie M
- 1Anderson, Andrea Marie
- 1Anderson-Baron, Matthew N
- 1Armstrong, Heather K
- 1Baier, Alicia
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Fall 2018
Cells require the ability to modulate function in response to their surroundings so that they are able to contribute to the survival of the organism. A key mechanism that allows tunable responses to changes in environment is by differential control of gene expression by transcriptional...
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Understanding the evolution of the membrane trafficking system in diverse eukaryotes through comparative genomics and transcriptomics
DownloadSpring 2018
Single-celled organisms represent the majority of eukaryotic diversity. Recent advances in sequencing technologies have been critical for understanding the evolutionary biology and cell biology of microbial eukaryotes. Comparative genomic analyses have shown that many genes that underlie...
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Spring 2019
In yeast, subtelomeric chromatin is silenced and positioned at the inner nuclear membrane (INM) through the interaction of proteins that comprise the heterotrimeric SIR complex with INM proteins. Telomeres reside primarily at the INM using partially redundant tethering mechanisms mediated by the...
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Spring 2012
Mast cells are tissue-resident immune cells that undergo exocytosis upon activation, releasing potent immunoregulatory molecules that initiate inflammatory responses. Here, I investigated the role of the hematopoietic specific Rho GTPase, Rac2, and the ubiquitous, Rac1, on mast cell exocytosis....
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Fall 2023
Adult hippocampal neurogenesis (AHN) involves generating hippocampal granule neurons and the subsequent integration of granule neurons into the hippocampus synaptic circuit. This continuous neuron generation supports ongoing learning and memory formation. Consequently, dysregulation of AHN and...
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The Peroxin Pex34p Functions with the Pex11 Family of Proteins to Regulate the Peroxisome Population in the Yeast Saccharomyces cervisiae
DownloadSpring 2012
Peroxisomes are highly dynamic organelles that change in size and number in response to both intra- and extracellular cues. Peroxisome growth and division are controlled by the import of matrix proteins and by a specialized divisional machinery that includes peroxisome-specific factors, such as...