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Fall 2019

Walker, Daniel B

This thesis examines the work of three artists—Beatriz da Costa, Tomás Saraceno, and Andrea Zittel—whose practices engage strategically with design in ways that echo pedagogical developments at the German Bauhaus and later at Black Mountain College. These two, short-lived, schools were known for...

Fall 2021

Hough, Cameron M.

Terahertz (THz) radiation is a non-ionizing form of electromagnetic (EM) energy that occupies a broad frequency region at the interface between conventional microwave and infrared bands. The strong coupling between THz excitations and natural oscillatory dynamics in biological systems has...

Fall 2019

Maplethorpe, Emily GD

Rare cancers affect few people individually, but collectively account for approximately 22% of new cancer cases in Canada. However, prevention and population-level research on rare cancers have been limited as low case numbers make them difficult to study. The emergence of large, collaborative...

Fall 2020

Menghisteab, Isaac

Exosomes and small microvesicles are types of small extracellular vesicle (sEVs) secreted by cancerous and normal cells. sEVs are filled with cargo from cancer cells that may affect both nearby and distant tissues. sEVs from colorectal cancers that enter blood vessels draining the intestine will...

Spring 2020

Moura Paiva, Igor

Active targeting strategies have been pursued to improve the efficacy and safety of cancer therapeutics and theranostics. The significant benefit of tumor homing ligands conjugated to small molecules versus nanoparticle delivery systems in enhancing drug delivery to the tumor is still a matter of...

Fall 2024

Pontillas, Shienna Marie A

Gene therapy offers a promising approach for treatment of a diverse array of diseases at their genetic root causes. The cationic polyethyleneimine (PEI) has been extensively used for successful non-viral nucleic acid delivery in experimental systems, but its clinical utility has been hampered by...

Spring 2024

Parkinson, Joanna F

Despite the large body of evidence of the benefits of exercise for people with cancer, it is often not part of standard care. This thesis addresses two components that are relevant to the widespread implementation of exercise oncology programs in clinical practice: cost-effectiveness and symptom...

Spring 2022

Ntoukas, Stephanie M

Background: Despite improvements in surgical neck dissection (ND) procedures, head and neck cancer survivors (HNCS) still endure acute and chronic side effects such as loss of muscular strength, limitations in physical functioning, and fatigue, that impact quality of life and limit return to...

Spring 2022

Bharadia, Morgan K

Background: Patients with cancer frequently use natural health products (NHPs) to help treat cancer, reduce side effects, or improve effectiveness of conventional cancer treatment, and improve their quality of life. Often oncology healthcare providers do not inquire about NHP use, leading to low...

Spring 2020

Dinakaran, Deepak

Radiotherapy is used in the treatment of 50% of all cancer patients. It has evolved into a high precision therapy in cancer care. Radiotherapy’s main limitation is the damage incurred on normal tissue. Advances in modern radiotherapy allowed for improved precision in delivery and optimizes its...