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Skip to Search Results- 1 Owttrim, George W.
- 1Anderson, Bailey
- 1Chen, Elizabeth J. Y.
- 1Fagan-Garcia, Katharine
- 1Griffiths, Cameron
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- 8Graduate and Postdoctoral Studies (GPS), Faculty of
- 8Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 2WISEST Summer Research Program
- 2WISEST Summer Research Program/WISEST Research Posters
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/Journal Articles (Biological Sciences)
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Spring 2014
This thesis examines the pathophysiology of asthma, attempts to determine the cellular mechanisms behind viral-induced immune memory mediated asthma exacerbations, and investigates urinary metabolomic biomarkers of asthma and neonatal hypoxia.
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Fall 2021
Poxviruses encode many genes that are orthologs of cellular genes. These orthologs serve many functions, but those that are of most interest are ones that have evolved further and now serve an immune-evasion function. Such genes were likely first acquired by poxviruses through some form of...
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Fall 2020
Infectious respiratory diseases, caused by viruses and bacteria that attack the respiratory system, constitute a serious threat in public health around the world. Pathogens can be transmitted in the air though large droplets or aerosols. As aerosols can linger in the environment for a prolonged...
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Invited major book review of M. Cannon & L. Sunseri, (2011), “Racism, Colonialism, and Indigeneity in Canada: A Reader”
Download2012
Book Review: Racism, Colonialism, and Indigeneity in Canada: A Reader, Edited by Martin J. Cannon and Lina Sunseri. Toronto: Oxford University Press Canada, 2011, paperback, 284 pages. ISBN 978-0-1954-3231-2
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Spring 2020
Respiratory syncytial virus (RSV) is a ubiquitous respiratory pathogen that infects almost everyone by the age of two. In high-risk populations, such as infants and elderly individuals, RSV can infect the lower respiratory tract and cause severe symptoms, such as bronchiolitis or pneumonia. As a...
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Inhibition and enhancement of Respiratory Syncytial Virus replication by nucleoside analogues and bis(indole) compounds
DownloadSpring 2019
Respiratory syncytial virus (RSV) is an Orthopneumovirus that infects the epithelium of the airways. Severe RSV infection of the lower respiratory tract in infants is a leading cause of pediatric hospitalizations. RSV also causes substantial morbidity in immunocompromised and elderly populations....
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Characterization of the cold stress-induced cyanobacterial DEAD-box protein CrhC as an RNA helicase
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Owttrim, George W., Yu, Esther
We have shown previously that CrhC is a unique member of the DEAD-box family of RNA helicases whose expression occurs specifically under conditions of cold stress. Here we show that recombinant His-tagged CrhC, purified from Escherichia coli, is an ATP-independent RNA binding protein possessing...
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Spring 2014
The introduction of WNV into North America in 1999 was followed by rapid spread throughout the continent. Today, WNV is an endemic pathogen in the west, with thousands of cases of severe infection reported annually. In addition to traditional vaccine research, there is an urgent need to...