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Carbon-on-Gold Films and Spontaneous Adsorption of Aryldiazonium Salts for Surface Plasmon Resonance Sensing
DownloadFall 2021
Over the past decades, surface plasmon resonance (SPR) technology has gained popularity as a powerful analytical technique for the study of biomolecular interactions and medical diagnostics. This is made possible thanks to the well-established gold-thiolate chemistry. However, the limited...
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Stimuli-Responsive Polymer-Based Devices for Surface Plasmon Resonance Spectrometer Sensing
DownloadSpring 2018
Surface plasmon resonance (SPR) has emerged as a powerful tool in sensing and biosensing for decades due to its label free and real-time data collection characteristics. In the first part of this thesis, a custom-built high performance SPR spectrometer with broad range of scanning angle, high...
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Spring 2015
Our primary goal of this study was to obtain a better understanding for the carbohydrates binding interactions with human intelectin (hIntL). Studying the binding specificity of hIntL could help in discovering its natural substrate and might give us a clue about its role in the innate immune...
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Spring 2018
Small-molecule metabolites (MW < 1,000 Da) are now emerging as an important type of biomarkers, thanks to the rapid development of systems biology such as metabolomics. Compared to nucleic acids and protein, metabolite is closer to the phenotype. Rapid detection and quantification of metabolites...