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Skip to Search Results- 3Short bowel syndrome
- 2Glucagon-like peptide-2
- 2Intestinal failure
- 1Animal model
- 1Bacterial translocation
- 1Bile acid
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Mechanisms of Neonatal Intestinal Failure-Associated Liver Disease: Exploring the Gut-Liver Axis
DownloadSpring 2018
Neonates with intestinal failure (IF), who must rely on parenteral nutrition (PN) for growth and maintenance of health, are at risk for intestinal failure-associated liver disease (IFALD). In neonates, short bowel syndrome (SBS) as a result of intestinal resection is the most common cause of IF....
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Role of Glucagon-like Peptide-2 and Elemental Formula in Short Bowel Syndrome – Using Neonatal Piglets as an Animal Model
DownloadSpring 2012
Recovery from short bowel syndrome (SBS) requires intestinal adaptation, dependent on enteral nutrition (EN) and peptides, like glucagon-like peptide-2 (GLP-2). The purpose of this thesis was to investigate endogenous GLP-2 production and compare elemental versus polymeric formula in a neonatal...
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Trophic peptide therapies for neonatal short bowel syndrome: actions and mechanisms studied in a preclinical model
DownloadFall 2016
Short bowel syndrome (SBS) occurs when a significant length of intestine is surgically resected for both congenital and acquired intestinal abnormalities and remains a significant cause of morbidity and mortality in neonates. With an insufficient amount of intestine available for nutrient...