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Skip to Search Results- 2Judy Gnarpe
- 1 Thayer, Edward C.
- 1Agustin, Roman, V
- 1Al-musawi, Maryam
- 1Anderson-Baron, Matthew N
- 1Berardi, Enrico
- 18Graduate and Postdoctoral Studies (GPS), Faculty of
- 18Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 3Agricultural, Food and Nutritional Science, Department of
- 3Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 3Biological Sciences, Department of
- 3Biological Sciences, Department of/Journal Articles (Biological Sciences)
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Development of technological alternatives to produce renewable fuels from oleaginous microorganisms
DownloadFall 2014
Microbial lipids are a promising feedstock for the production of renewable fuels. However, use of microbial lipids has been hindered due to challenges in the cultivating and processing of microbes. Thus, innovative technologies are required to enhance the feasibility of integrating oleaginous...
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An ancestral role in de novo peroxisome assembly is retained by the divisional peroxin Pex11 in the yeast Yarrowia lipolytica
DownloadFall 2014
This thesis is on peroxisome evolution and reports my findings with regard to two major aspects of this process. First, I investigated the evolution of a peroxisomal protein family for which large expansions had been noted in diverse eukaryotes from a comparative genomic perspective and combined...
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A comprehensive assessment of peroxisome biology: ER-dependent peroxisome proliferation control, evolution of organelle inheritance in yeast and a Drosophila model system of Zellweger syndrome
DownloadFall 2013
The modern eukaryotic cell is a meshwork of encapsulating membranes that compartmentalize many distinct biochemical processes. It is complex. This complexity facilitates the many unique and diverse processes that aid the eukaryote in its growth, division and adaptation to its environment. A...
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A role for the nuclear pore complex protein Nup170p in defining chromatin structure and regulating gene expression
DownloadSpring 2012
The spatial organization of chromosomal loci within the nucleus can have a significant influence on transcriptional activity. Transcriptionally active genes are generally positioned within the nuclear interior. By contrast, the positioning of genes at the nuclear periphery is often correlated...
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2012
Müller-Reichert, T., Greenan, G., O'Toole, E., Srayko, M., Lange, K.I.
As part of a multi-subunit ring complex, γ-tubulin has been shown to promote microtubule nucleation both in vitro and in vivo, and the structural properties of the complex suggest that it also seals the minus ends of the polymers with a conical cap. Cells depleted of γ-tubulin, however, still...
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Exploring the role of the thioredoxin system, peroxiredoxins and glutaredoxins in aluminum and cadmium tolerance in yeast and Arabidopsis thaliana
DownloadFall 2011
Aluminum (Al) and cadmium (Cd) are non-redox active metal ions of agricultural importance. Both are able to induce oxidative damage as a mechanism of toxicity. To increase our understanding of the mechanisms of Al and Cd toxicity and tolerance in plants, the potential role of antioxidant enzymes...
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Hsp90 and its co-chaperones regulate the activity of human Argonaute2 in RNA-mediated silencing pathways
DownloadFall 2011
The potent ability of small, double-stranded RNAs to silence gene expression was initially reported 1998, sparking revolutions in molecular biology and genetics. Since then, intensive research into the mechanism of RNA-mediated silencing has implicated the machinery of this pathway in the...
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Functional and Topological Analysis of Acyl-CoA:Diacylglycerol Acyltransferase 2 From Saccharomyces cerevisiae
DownloadSpring 2011
Acyl-CoA:diacylglycerol acyltransferase (EC 2.3.1.20, DGAT or DAGAT) is a membrane protein found mainly in the endoplasmic reticulum (ER). It catalyzes the final step in the biosynthesis of triacylglyerol (TAG or TG), which is the principal repository of fatty acids for energy utilization and...
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2010
Rachubinski, R.A., Fagarasanu, A., Mast, F.D.
Peroxisomes can import large multimeric protein complexes and even 9-nm gold particles decorated with peroxisome-targeting signals. They achieve these feats of protein passage using a distinctive translocon whose highly dynamic aqueous pore can expand to accommodate the increasing girths of...
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Fall 2010
Peroxisomes are indispensable organelles that perform many essential metabolic activities. Thus, eukaryotic cells have evolved molecular mechanisms to ensure the inheritance of peroxisomes from mother cell to daughter cell at cell division. In the budding yeast Saccharomyces cerevisiae, the class...