Search
Skip to Search Results- 1Ali, D.W.
- 1Alvarado, Laura
- 1Currie, P. J.
- 1De Serres, Sophie Jeannine.
- 1Drapeau, P.
- 1Griener, Anna L
-
A pilot study investigating arm and leg FES-assisted cycling as an intervention for improving ambulation after Incomplete Spinal Cord Injury
DownloadSpring 2013
People with incomplete spinal cord injury (iSCI) have the potential for recovering walking through plasticity-induced changes in the remaining neural circuitry. Current rehabilitation for walking attempts to induce such changes by providing relevant sensory inputs and motor commands through...
-
Characterization of WT1-expressing interneurons and investigation of their role in locomotion
DownloadFall 2019
Mammalian locomotion is controlled by a specialized neural network, known as the locomotor central pattern generator (CPG), which is situated entirely within the ventral spinal cord. A number of studies completed over the past two decades have indicated that this neural network is comprised of...
-
Connectivity and Regional Distribution of Constituent Cells of the Mammalian Locomotor Central Pattern Generator
DownloadFall 2016
The mammalian spinal cord contains a network of neurons capable of generating the rhythm and coordinating the complex motor pattern which underlies overground locomotion. This network, called the locomotor central pattern generator (CPG), can operate in isolation from afferent input and...
-
Dinosaur speed demon: the caudal musculature of Carnotaurus sastrei and implications for the evolution of South American abelisaurids
Download2011
Currie, P. J., Persons IV, W. S.
In the South American abelisaurids Carnotaurus sastrei, Aucasaurus garridoi, and, to a lesser extent Skorpiovenator bustingorryi, the anterior caudal ribs project at a high dorsolateral inclination and have interlocking lateral tips. This unique morphology facilitated the expansion of the caudal...
-
Recovery from open channel block by acetylcholine during neuromuscular transmission in larval zebrafish
Download2000
Legendre, P., Ali, D.W., Drapeau, P.
At larval zebrafish neuromuscular junctions (NMJs), miniature end plate currents (mEPCs) recorded in vivo have an unusually fast time course. We used fast-flow application of acetylcholine (ACh) onto outside-out patches to mimic the effect of synaptic release onto small numbers of ACh receptor...
-
Fall 2013
As a general rule, larger-bodied animals within a species move at faster absolute speeds independently of locomotive mode. The relationship between body size and speed in sea stars is decidedly less clear. One species of sea star follows the general trend, three species show no correlation...
-
The Study of Hereditary Spastic Paraplegia Genes Using Drosophila Homologues: Behavioural Insights
DownloadFall 2014
Hereditary Spastic Paraplegia (HSP) denotes a heterogeneous group of heritable neurodegenerative disorders predominantly characterized by progressive weakness and spasticity of the legs. Mutations in the gene SPAST are by far the most common, while mutations in the gene ATL1 are the second most...
-
Fall 2011
The locomotor Central Pattern Generator (CPG) is a neuronal network capable of producing rhythmic locomotor output independent of sensory or descending input. Attempts to identify component interneurons of the CPG have been aided by the discovery of transcription factors that are expressed by...