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Characterization of eNOS-based Platelets Subpopulations in COVID-19 and the Impact of Platelet α-Granule Contents on Cancer Cell PD-L1
DownloadFall 2024
Thrombosis significantly complicates numerous diseases that have inflammatory components. This condition, characterized by the formation of blood clots within blood vessels, can exacerbate a range of health issues, from cardiovascular diseases to systemic infections like COVID-19, and even...
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2012
Radziwon-Balicka, A., Jurasz, P., Moncada de la Rosa, C.
Platelets, in addition to maintaining hemostasis, also stimulate angiogenesis by generating and releasing, upon activation, factors that promote the growth of new blood vessels. To date, at least 20 angiogenesis-regulating factors have been identified in platelets, including both promoters and...
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Revisiting the antifibrinolytic effect of carboxypeptidase N: novel structure and regulation
DownloadFall 2010
Carboxypeptidase N (CPN) is a plasma carboxypeptidase that was discovered in the 1960s as a regulator of inflammation and vascular tone. Through the removal of carboxy-terminal basic residues, CPN alters the activity or binding specificity of inflammatory mediators and vasoactive peptides. CPN...