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2015

Sällman Almén, M., Liao, X., Stothard, P., Henegar, C., Van Doormaal, B., Rubin, C. -J., Andersson, L., Barsh, G. S., Ito, S., Plastow, G., Wakamatsu, K., Dorshorst, B.

Coat color in Holstein dairy cattle is primarily controlled by the melanocortin 1 receptor (MC1R) gene, a central determinant of black (eumelanin) vs. red/brown pheomelanin synthesis across animal species. The major MC1R alleles in Holsteins are Dominant Black (MC1RD) and Recessive Red (MC1Re). A...

2012

Wang, Lusheng, Moore, Steve S., Cai, Zhipeng, Goebel, Randy, Lin, Guohui, Wang, Yining, Stothard, Paul

Background Single nucleotide polymorphism (SNP) genotyping assays normally give rise to certain percents of no-calls; the problem becomes severe when the target organisms, such as cattle, do not have a high resolution genomic sequence. Missing SNP genotypes, when related to target traits, would...

2016-02-22

Miar, Younes, Wang, Zhiquan, Kemp, Robert A., Boddicker, Nicholas, Yang, Tianfu, Plastow, Graham, Zhang, Chunyan, Charagu, Patrick, Bruce, Heather

Of all the meat quality traits, tenderness is considered the most important with regard to eating quality and market value. In this study we have utilised genome wide association studies (GWAS) for peak shear force (PSF) of loin muscle as a measure of tenderness for 1,976 crossbred commercial...

Fall 2016

Davidson, Chelsea L

Leukocyte Ig-like Receptor 1 (LILRB1) is an inhibitory receptor expressed on a number of immune cells. The expression profile on NK cells is variable between people, with a range of 25-80% of NK cells expressing LILRB1. We previously uncovered a correlation between genotype within the 5’ end of...

2009

Xu, J., Goebel, R. A., Cai, Z., Sabaai, H., Lin, G., Wang, Z., Wang, Y., Stothard, P.

Background The \"common disease – common variant\" hypothesis and genome-wide association studies have achieved numerous successes in the last three years, particularly in genetic mapping in human diseases. Nevertheless, the power of the association study methods are still low, in particular on...

2005

Sperling, F. A. H., Dosdall, L. M., Laffin, R. D.

Ceutorhynchus neglectus Blatchley is a weevil that is native to, and widely distributed in, North America. It has life-history characteristics similar to its alien invasive congener, Ceutorhynchus obstrictus (Marsham), the cabbage seedpod weevil. Our study was undertaken to compare the population...