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2012

Steele, Michael A., Plaizier, Jan C., AlZahal, Ousama, Dionissopoulos, Louis, McBride, Brian W.

The objective of this study was to characterize the mRNA and protein expression of inflammatory and structural genes in the rumen epithelium during grain-induced ruminal acidosis in lactating dairy cattle. A total of 16 rumen-fistulated, lactating Holstein dairy cattle (618±35 kg of body weight,...

2005-09-01

Zhang, Xiuqing , Bolund, Lars , Bao, Jingyue , Ma, Ligeng , Wong, Gane K., Deng, Xing Wang , Wang, Jian , Liu, Xigang , Yuan, Longping , Li, Jian , Zhao, Hongyu , Pedersen, Soren , Wang, Xiangfeng , Wang, Jun , Sun, Ning , Cao, Mengliang , Chen, Chen , Jiao, Yuling , Li, Lin , Su, Ning

2008

Owttrim, G.W., Lalonde, S.V., Smith, D.S., Konhauser, K.O.

Bacteria grow in complex solutions where the adsorption of aqueous species and nucleation of mineral phases on the cell surface may interfere with membrane-dependent homeostatic functions. While previous investigations have provided evidence that bacteria may alter their surface chemical...

2012

Guan, Leluo, Romao, Josue M., McAllister, Tim, He, Maolong, Jin, Weiwu

Background MicroRNAs (miRNAs) are a class of molecular regulators found to participate in numerous biological processes, including adipogenesis in mammals. This study aimed to evaluate the differences of miRNA expression between bovine subcutaneous (backfat) and visceral fat depots (perirenal...

2009

Bell, J. B., Deng, H., Simmonds, A. J., Hughes, S. C.

Abstract: Vertebrate development requires the activity of the myocyte enhancer factor 2 (mef2) gene family for muscle cell specification and subsequent differentiation. Additionally, several muscle-specific functions of MEF2 family proteins require binding additional cofactors including members...

Fall 2011

Meng, Ya

Microarrays are biotechnological advancements measuring expressions of thousands of genes in a single assay. A two-group microarray study yields gene expression measurements for patients with a disease of interest and for healthy controls. Our objective is to apply the methods of microarray data...

2012

Owttrim, George W., Chamot, Danuta, Rosana, Albert R. R.

RNA helicases are ubiquitous enzymes whose modification of RNA secondary structure is known to regulate RNA function. The pathways controlling RNA helicase expression, however, have not been well characterized. Expression of the cyanobacterial RNA helicase, crhR, is regulated in response to...

2013

Steele, Michael A., Greenwood, Sabrina L., Plaizier, Jan C., McBride, Brian W., Matthews, James C., Laarman, Anne H., AlZahal, Ousama, Dionissopoulos, Louis

Subacute Ruminal Acidosis (SARA) is a disorder in cattle which can lead to chronic inflammation in the rumen epithelium, known as rumenitis. Butyrate has been shown to attenuate some of the detrimental effects of inflammatory gastroenteral disorders but the molecular mechanisms mediated by...

2014

Dobrinsky, John, Zhou, Chi, Dixon, Walter T., Dyck, Michael K., Stothard, Paul, Foxcroft, George R., Tsoi, Stephen, Verstegen, John

The in vitro production of early porcine embryos is of particular scientific and economic interest. In general, embryos produced from in vitro Assisted Reproductive Technologies (ART) manipulations, such as somatic cell chromatin transfer (CT) and parthenogenetic activation (PA), are less...

Fall 2014

Harrison, Tyler J

Optical imaging has long been a gold standard for medical imaging. However, due to the high optical scattering in tissues, it has not been possible to image deeper than a few wavelengths with a useful resolution. Photoacoustic imaging - the use of short-pulsed lasers to induce an ultrasound...