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Skip to Search Results- 5Serpe, Michael J.
- 4Löbenberg, Raimar
- 3Azarmi, Shirzad
- 3Roa, Wilson H.
- 2Finlay, W. H.
- 2Gao, Yongfeng
- 56Graduate and Postdoctoral Studies (GPS), Faculty of
- 56Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 6Pharmacy and Pharmaceutical Sciences, Faculty of
- 6Pharmacy and Pharmaceutical Sciences, Faculty of/Journal Articles (Pharmacy and Pharmaceutical Sciences)
- 4Chemistry, Department of
- 4Chemistry, Department of/Journal Articles (Chemistry)
- 56Thesis
- 8Article (Published)
- 3Report
- 2Research Material
- 1Article (Draft / Submitted)
- 1Conference/Workshop Poster
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Spring 2014
A new aerosol particle classifier, the Aerodynamic Aerosol Classifier (AAC), is presented with some of its applications. The instrument uses a centrifugal force and sheath flow between two concentric rotating cylinders to produce a monodisperse aerosol classified by aerodynamic diameter. Since...
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Anti-Cancer Mechanism of Trastuzumab via Blocking Nuclear HER2 Function and Epigenetic Mechanism of Resistance
DownloadSpring 2020
HER2 receptor tyrosine kinase (encoded by ERBB2 gene) is overexpressed in approximately 25% of all breast cancer tumors (known as HER2-positive breast cancers). Overexpression of HER2 causes overactivation of downstream receptor tyrosine kinase pathways including PI3K/Akt and MAPK pathways and is...
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Aquatic nanotoxicity testing: Insights at the biochemical, cellular, and whole animal levels
DownloadFall 2013
Aquatic organisms are susceptible to waterborne nanoparticles and there is only limited understanding of the mechanisms by which these emerging contaminants affect biological processes. The unique properties of nanomaterials necessitate evaluation of standard toxicity testing techniques to...
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Fall 2010
The purpose of this project was to formulate, modify and evaluate nanoparticles for targeting asialoglycoprotein receptor found in large numbers exclusively on hepatocyte surfaces. Our goal is to increase the efficacy, reduce the side effects and the cost of the hydrophilic drugs administered to...
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Spring 2021
A thorough overview of esters and their reductions is presented. A large focus was placed on reductions via homogeneous catalytic hydrogenation. Although several ester hydrogenation systems have been developed, the production of highly enantioenriched alcohols has generally relied upon the usage...
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Benign-by-Design: Synthesis of Engineered Silicon Nanoparticles and their Application to Oil Sands Water Contaminant Remediation
Download2013-11-29
Iqbal, M., Veinot, J.G.C., Purkait, T.K., Goss, G.G.
Oil sands are naturally occurring mixtures of sand or clay, water, fine silts, and bitumen. The oil sands extraction process consumes large volumes of water (i.e., ca. 3 barrels of fresh water for every 1 barrel of oil). Following the extraction of bitumen from the oil sands, a tailings slurry...
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Spring 2011
Selective ring opening of naphthenic molecules is a preferred reaction to increase cetane number of fuels, and it should result in products with no loss in molecular weight and longer alkyl side chains. Benzocyclopentane (indan) ring opening was studied under hydrogen atmospheric pressure at 609...
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Fall 2017
Chicken feathers are byproduct of poultry industries and except some minor low end application, they are generally dumped into landfills. An effort has been made to utilize this by-product by transforming them into nano-reinforced bioplastics which is not only a solution to feather waste disposal...
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Spring 2011
The objective of this thesis is to design nanoparticle (NP)-based drug delivery systems suitable for treatment of bone diseases. Two types of nanocarriers, (1) polymer coated bovine serum albumin (BSA) NPs and (2) lipid based NPs (micelles and liposomes) were investigated. The BSA NPs were...