Search
Skip to Search Results- 7Population-genetics
- 6Gene expression
- 3Dispersal
- 13'mRNA sequencing
- 1Adaptive variation
- 1Adipogenesis
- 3Cooke, Janice E. K.
- 3Lunney, Joan K.
- 2Coltman, David W.
- 2Harding, John C. S.
- 2Plastow, Graham S.
- 2Sperling, Felix A. H.
- 5Biological Sciences, Department of
- 5Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 4The NSERC TRIA Network (TRIA-Net)
- 4The NSERC TRIA Network (TRIA-Net)/Journal Articles (TRIA-Net)
- 3PigGen Canada
- 3PigGen Canada/Journal Articles
-
2013-01-01
Basu, Urmila, Josue, Romao Moura, Guan, LeLuo
The recent technological innovations in the area of functional genomics, gene expression/transcriptomic profiling can provide new insights to understand the molecular basis of adipogenesis. The focus of this review is to highlight the recent advances in our understanding of the complex interplay...
-
Birds of a feather do not always lek together: Genetic diversity and kinship structure of Greater Sage-Grouse (Centrocercus urophasianus) in Alberta
Download2010
Aldridge, C.L., Bush, K.L., Coltman, D.W., Carpenter, J.E., Paszowski, C.A., Boyce, M.S.
Endangered species are sensitive to the genetic effects of fragmentation, small population size, and inbreeding, so effective management requires a thorough understanding of their breeding systems and genetic diversity. The Greater Sage-Grouse (Centrocercus urophasianus) is a lekking species that...
-
Differences in Whole Blood Gene ExpressionAssociated with Infection Time-Course andExtent of Fetal Mortality in a ReproductiveModel of Type 2 Porcine Reproductive andRespiratory Syndrome Virus (PRRSV)Infection
Download2016-04-19
Wilkinson, Jamie M., Ladinig, Andrea, Bao, Hua, Kommadath, Arun, Stothard, Paul, Lunney, Joan K., Harding, John C. S., Plastow, Graham S.
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnantfemales causes fetal death and increased piglet mortality, but there is substantial variationin the extent of reproductive pathology between individual dams. This study used RNA-sequencing to characterize the whole...
-
Differential responses in placenta and fetal thymus at 12 days post infection elucidate mechanisms of viral level and fetal compromise following PRRSV2 infection
Download2020-01-01
Van Goor, Angelica, Pasternak, Alex, Walker, Kristen, Hong, Linjun, Malgarin, Carolina, MacPhee, Daniel J., Harding, John C. S., Lunney, Joan K.
Background:A pregnant gilt infected with porcine reproductive and respiratory syndrome virus (PRRSV) can transmit the virus to her fetuses across the maternal-fetal-interface resulting in varying disease outcomes. However,the mechanisms leading to variation in fetal outcome in response to PRRSV...
-
2012
Meghen, C. N., Platz, S. S., Hu, X. S., Moore, S. S., Simila, J., Plastow, G.
Estimating animal abundance in industrial scale batches of ground meat is important for mapping meat products through the manufacturing process and for effectively tracing the finished product during a food safety recall. The processing of ground beef involves a potentially large number of...
-
How the mountain pine beetle (Dendroctonus ponderosae) breached the Canadian Rocky Mountains
Download2014-01-01
Sperling, Felix A. H., Murray, Brent W., Li, Yisu, Coltman, David W., Bohlmann, Joerg, Janes, Jasmine K., Cooke, Janice E. K., Boone, Celia K., Huber, Dezene P.W., Keeling, Christopher I., Yuen, Macaire M. S.
The mountain pine beetle (MPB; Dendroctonus ponderosae Hopkins), a major pine forest pest native to western North America, has extended its range north and eastward during an ongoing outbreak. Determining how the MPB has expanded its range to breach putative barriers, whether physical...
-
Identification of genes and gene expression associated with dispersal capacity in the mountain pine beetle, Dendroctonus ponderosae Hopkins (Coleoptera: Curculionidae)
Download2021-07-01
Shegelski, Victor A., Evenden, Maya L., Huber, Dezene P. W., Sperling, Felix A. H.
Dispersal flights by the mountain pine beetle have allowed range expansion and major damage to pine stands in western Canada. We asked what the genetic and transcriptional basis of mountain pine beetle dispersal capacity is. Using flight mills, RNA-seq and a targeted association study, we...
-
Linking genotype to phenotype to identify genetic variation relating to host susceptibility in the mountain pine beetle system
Download2020-01-01
Cullingham, Catherine I., Peery, Rhiannon M., Fortier, Colleen E., Mahon, Elizabeth L., Cooke, Janice E. K., Coltman, David W.
Identifying genetic variants responsible for phenotypic variation under selective pressure has the potential to enable productive gains in natural resource conservation and management. Despite this potential, identifying adaptive candidate loci is not trivial, and linking genotype to phenotype is...
-
Mitochondrial DNA variation and identification of bark weevils in the Pissodes strobi species group in western Canada (Coleoptera: Curculionidae)
Download1995
Sperling, F. A. H., Langor, D. W.
Abstract: Morphological, allozyme, and chromosomal characters and ecological traits have limited value for discriminating among four closely related Pissodes spp. known from western Canada. We amplified a 1585-bp segment of mitochondrial DNA (mtDNA), including half of the cytochrome oxidase I...