Search
Skip to Search Results- 6Biochemistry, Department of
- 6Biochemistry, Department of/Journal Articles (Biochemistry)
- 5Graduate and Postdoctoral Studies (GPS), Faculty of
- 5Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 3Chemistry, Department of
- 3Chemistry, Department of/Journal Articles (Chemistry)
-
Fall 2019
Cilia are microtubule-based structures that project from nearly every cell in the vertebrate body. While cilia in different contexts can have either sensory or motile functions, all cilia rely upon a core set of genes. When these genes are mutated either singly or in various combinations, a...
-
Mitogen-activated protein kinase-dependent activation of the na+/H+ exchanger is mediated through phosphorylation of amino acids ser(770) and ser(771)
Download2007-01-01
Malo, Mackenzie E., Li, Liang, Fliegel, Larry
We investigated regulation of the type 1 isoform of the Na+/H+ exchanger by phosphorylation. Four specific groups of serine and threonine residues in the regulatory carboxyl-terminal tail were mutated to alanine residues: group 1, S693A; group 2, T718A and S723A/S726A/S729A; group 3,...
-
Narrating Identity: The impact of literary reading on storied autobiographical memory development
DownloadSpring 2019
This dissertation describes the development and validation of a questionnaire (Narrating Identity Questionnaire; NIQ) that captures the differential contribution of expressive and integrative forms of literary reading on narrating identity development (storied autobiographical memory – Goldie,...
-
2014
Serpe, Michael J., Islam, Molla R.
In this submission we fabricated a humidity-responsive polymer-based actuator by layering negatively charged poly(N-isopropylacrylamide)-co-acrylic acid microgels and positively charged poly(diallyldimethyl ammonium chloride) on top of a flexible plastic substrate. We show that the extent of the...
-
Structural and functional analysis of transmembrane segment VI of the NHE1 isoform of the na+/H+ exchanger
Download2009-01-01
Tzeng, Jennifer, Lee, Brian L., Sykes, Brian D., Fliegel, Larry
The Na+/H+ exchanger isoform 1 is a ubiquitously expressed integral membrane protein. It resides on the plasma membrane of cells and regulates intracellular pH in mammals by extruding an intracellular H+ in exchange for one extracellular Na+. We characterized structural and functional aspects of...
-
Structural and functional analysis of transmembrane XI of the NHE1 isoform of the na+/H+ exchanger
Download2009-01-01
Lee, Brian L., Li, Xiuju J., Liu, Yongsheng, Sykes, Brian D., Fliegel, Larry
The Na+/H+ exchanger isoform 1 is a ubiquitously expressed integral membrane protein that regulates intracellular pH in mammals by extruding an intracellular H+ in exchange for one extracellular Na+. We characterized structural and functional aspects of the critical transmembrane (TM) segment XI...
-
Turbidity Mitigation in an Oil Sands End Pit Lake through pH Reduction and Fresh Water Addition
DownloadFall 2016
The remediation of oil sands wastes such as fluid fine tailings (FFT) and oil sands process-affected water (OSPW) are of increasing concern in the oil sands industry. End pit lakes are one remediation option currently being researched at commercial scale in Base Mine Lake (BML) operated by...