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Skip to Search Results- 14Graduate and Postdoctoral Studies (GPS), Faculty of
- 14Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 6Biochemistry, Department of
- 6Biochemistry, Department of/Journal Articles (Biochemistry)
- 3Chemistry, Department of
- 3Chemistry, Department of/Journal Articles (Chemistry)
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Structural and functional analysis of transmembrane XI of the NHE1 isoform of the na+/H+ exchanger
Download2009-01-01
Lee, Brian L., Li, Xiuju J., Liu, Yongsheng, Sykes, Brian D., Fliegel, Larry
The Na+/H+ exchanger isoform 1 is a ubiquitously expressed integral membrane protein that regulates intracellular pH in mammals by extruding an intracellular H+ in exchange for one extracellular Na+. We characterized structural and functional aspects of the critical transmembrane (TM) segment XI...
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2002
Clark, A.M., MacIntyre, P.D., Sharp, C.
Access to health care should be determined by clinical need and not by age. Older people form an increasing proportion of the general population and of those with coronary heart disease, but compared with younger people they are less likely to be invited for cardiac rehabilitation programmes and...
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Spring 2011
The traditional PI3K pathway relies on agonist mediated stimulation of PI3Kα through RTKs and PI3Kγ through GPCRs, which stimulate downstream enzymes such as Akt. This pathway has been found to be important in cardiomyocytes and cardiofibroblasts for regulating cardiac morphology and function....
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Fall 2012
Heart disease is a leading cause of morbidity and mortality in the world with a growing prevalence in a variety of manifestations. Many of the events that occur in the heart during the progression of disease have been explored to identify a causative mechanism to develop effective treatments and...
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Turbidity Mitigation in an Oil Sands End Pit Lake through pH Reduction and Fresh Water Addition
DownloadFall 2016
The remediation of oil sands wastes such as fluid fine tailings (FFT) and oil sands process-affected water (OSPW) are of increasing concern in the oil sands industry. End pit lakes are one remediation option currently being researched at commercial scale in Base Mine Lake (BML) operated by...
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Fall 2023
Thump Thump. Swoosh, swoosh. Kamlamunikk. Heart. Mi’kmaq teachings of heart are tied to concepts such as moontime, spirits, ancestors and blood knowledge. Being a Mi’kmaq woman from the west coast of Newfoundland with strong lifelong community connection I was aware that the understanding of...