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- 2Bao, H.
- 2Basu, Urmila
- 2Chan, Catherine B.
- 2Dionissopoulos, Louis
- 2Dixon, Walter T.
- 22Graduate and Postdoctoral Studies (GPS), Faculty of
- 22Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 13Biological Sciences, Department of
- 13Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 12Agricultural, Food and Nutritional Science, Department of
- 12Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 9Department of Agricultural, Food, and Nutritional Science
- 2Department of Biological Sciences
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- 1Department of Cell Biology
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- 2Damaraju, Sambasivarao (Laboratory Medicine and Pathology)
- 1Baracos, Vickie (Oncology)
- 1Belosevic, Miodrag (Biological Sciences)
- 1Dinu, Irina (Department of Public Health Sciences)
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Commensal bacteria and expression of two major intestinal chemokines, TECK/CCL25 and MEC/CCL28, and their receptors
Download2007
Gerdts, Volker, Meurens, Francois, Willing, Benjamin P., Berri, Mustapha, Siggers, Richard H., Van Kessel, Andrew G., Salmon, Henri
Background CCL25/TECK and CCL28/MEC are CC chemokines primarily expressed in thymic dendritic cells and mucosal epithelial cells. Their receptors, CCR9 and CCR10, are mainly expressed on T and B lymphocytes. In human, mouse, pig and sheep CCL25 and CCL28 play an important role in the segregation...
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Comparative transcriptomic analysis of rectal tissue from beef steers revealed reduced host immunity in Escherichia coli O157:H7 super-shedders
Download2016-03-09
McAllister, Tim A., Wang, Ou, Plastow, Graham, Stanford, Kim, Liang, Guanxiang, Guan, Le L., Selinger, Brent
Super-shedder cattle are a major disseminator of E. coli O157:H7 into the environment, and the terminal rectum has been proposed as the primary E. coli O157:H7 colonization site. This study aimed to identify host factors that are associated with the super-shedding process by comparing...
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Detecting, correcting, and preventing the batch effects in multi-site data, with a focus on gene expression Microarrays
DownloadSpring 2014
Gene expression microarrays are widely used to better understand the complex biological mechanisms inside cells. One of the main obstacles of applying statistical learning algorithms to microarray data is the large gap between the number of features (p) and the number of available instances (n),...
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Differences in whole blood gene expression associated with infection time-course and extent of fetal mortality in a reproductive model of type 2 porcine reproductive and respiratory syndrome virus (PRRSV) infection
Download2016
Ladinig, Andrea, Stothard, Paul, Wilkinson, Jamie M., Kommadath, Arun, Plastow, Graham S., Harding, John C. S., Bao, Hua, Lunney, Joan K.
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnant females causes fetal death and increased piglet mortality, but there is substantial variation in the extent of reproductive pathology between individual dams. This study used RNA-sequencing to characterize the whole...
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Differential expression of miRNAs in Brassica napus root following infection with Plasmodiophora brassicae
Download2014
Basu, Urmila, Verma, Shiv, Rahman, Muhammad H., Deyholos, Michael K., Kav, Nat N. V.
Canola (oilseed rape, Brassica napus L.) is susceptible to infection by the biotrophic protist Plasmodiophora brassicae, the causal agent of clubroot. To understand the roles of microRNAs (miRNAs) during the post-transcriptional regulation of disease initiation and progression, we have...
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Disentangling detoxification: Gene expression analysis of feeding mountain pine beetle illuminates molecular-level host chemical defense detoxification mechanisms
Download2013-01-01
Bohlmann, Jörg, Bonnett, Tiffany R., Pitt, Caitlin, Keeling, Christopher I., Yuen, Macaire M. S., Huber, Dezene P. W., Robert, Jeanne A.
The mountain pine beetle, Dendroctonus ponderosae, is a native species of bark beetle (Coleoptera: Curculionidae) that caused unprecedented damage to the pine forests of British Columbia and other parts of western North America and is currently expanding its range into the boreal forests of...
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2008
Faulkner, S.G., Tonn, W.M., Schmitt, D.R., Welz, M.
Blasting in or near water can negatively affect fish. In Canada, there are maximum allowable limits for blasting-induced overpressure (100 kPa) and peak particle velocity (PPV; 13 mm/s) to protect fish and their incubating eggs, respectively. No studies, however, have related PPVs from blasting...
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Elucidating the effects of photoperiod during gestation and lactation on mammary gene expression and function in cows and mice
DownloadSpring 2015
Photoperiod, or day length, generates a highly accurate biological calendar that allows animals to anticipate and adapt to environmental change throughout the year. Photoperiod coordinates both daily and yearly rhythms associated with sleep/wake cycles, behavior, and reproduction, including...
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Environmental particulate matter induces murine intestinal inflammatory responses and alters the gut microbiome
Download2013-01-01
Thiesen, Aducio, Rioux, Kevin P., Tso, Robert, Kish, Lisa, Barkema, Herman W., Madsen, Karen L., Vincent, Renaud, Wine, Eytan, Kaplan, Gilaad G., Hotte, Naomi, Gänzle, Michael G.
Background Particulate matter (PM) is a key pollutant in ambient air that has been associated with negative health conditions in urban environments. The aim of this study was to examine the effects of orally administered PM on the gut microbiome and immune function under normal and inflammatory...
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Fall 2012
Sub-acute ruminal acidosis is a digestive disorder experienced by animals fed a high grain diet, and causes substantial economic loss to the dairy industry. The objective of this research was to evaluate novel approaches to manage and prevent sub-acute ruminal acidosis. In Study 1, I found that...