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Skip to Search Results- 1Asomaning, Justice
- 1Coleman, Robert J.
- 1Curtis Pahara, Donna
- 1Fillmore, Natasha
- 1Hargreaves, Katharine Mary.
- 1McNamara, Allison M
- 7Department of Agricultural, Food, and Nutritional Science
- 3Department of Oncology
- 2Department of Medicine
- 2Department of Pharmacology
- 1Department of Biological Sciences
- 1Department of Food Science
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Baker, Kristi (Oncology)
- 1Bressler, David C. (Agricultural, Food and Nutritional Science)
- 1Dr. Michael Dyck (Department of Agricultural, Food, and Nutritional Science)
- 1Dyck, Jason RB (Pediatrics)/ McAlister, Finlay A (Medicine)
- 1Febbraio,Maria (Dentistry)
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Design and synthesis of renewable lipid-based nanocarriers with thermosensitivity for targeted drug delivery applications
DownloadSpring 2024
Numerous drug molecules currently available on the market suffer from short half-life, in vivo instability, poor bioavailability, rapid degradation and inappropriate distribution. While nanocarriers have emerged as a promising solution to address these issues, the primary objective and challenge...
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Fall 2016
Multiple sources suggest that insulin resistance and derangements of cardiac metabolism are among the earliest signs of type-2 diabetes detected in the heart. Unfortunately, limited evidence reflects early changes in cardiac mitochondrial metabolism linked to the development of this disease....
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Spring 2016
Heart failure is associated with major changes in cardiac energy metabolism that decrease cardiac efficiency, which can reduce cardiac function. In severe heart failure there is a shift back toward a fetal heart metabolism, with a decrease in mitochondrial oxidative metabolism and increase in...
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Growth of oleaginous yeasts on mixed C5 and C6 sugar streams to generate lipid feedstocks for renewable hydrocarbon production
DownloadSpring 2022
Microbial lipids are a promising feedstock to produce renewable fuels. Lignocellulosic feedstocks can provide multiple carbon sources for microbial growth, such as hexoses (C6) and pentoses (C5). Oleaginous yeasts can convert C5 and C6 sugars to microbial lipids that can be further processed into...
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Litter birth weight phenotype and maternal n-3 long-chain polyunsaturated fatty acid supplementation in pigs
DownloadSpring 2013
Research reported in this thesis investigated effects of n-3 polyunsaturated fatty acid (LCPUFA) supplementation, litter birth weight phenotype, and their possible interactions, on reproductive performance of the gilt and sow and postnatal performance of the litter. In an initial study, LCPUFA...
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Mapping and characterization of mel-43(sb41), a gene required for early embryonic viability in C. elegans
DownloadSpring 2010
A genetic screen for dominant, temperature-sensitive, maternal-effect embryonic lethal mutations identified mel-43(sb41), a gene required for early embryonic viability (Mitenko et al., 1997). Linkage mapping placed mel-43 within a small region on chromosome IV. Genetic analyses suggested that...
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New Insight into the Role of Myocardial Fatty Acid Uptake and Utilization in Health and Disease
DownloadFall 2013
All mammalian cells rely on adenosine triphosphate (ATP) to maintain function and for survival. The heart has the highest basal ATP demand of any organ due to the necessity for continuous contraction. As such, the ability of the cardiomyocyte to monitor cellular energy status and adapt the supply...