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- 10Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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- 3Medicine and Dentistry, Faculty of/Alliance for Canadian Health Outcomes in Diabetes
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Development of Oral Influenza Vaccine Delivery System Utilizing pH Responsive Pored Microparticles
DownloadFall 2015
Influenza is a major respiratory disease caused by influenza virus. Recent spread of the extremely pathogenic avian and swine influenza viruses paint a morbid picture of the emergence of a more lethal influenza virus in future. Currently, hypodermic needles are being dominantly employed in...
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Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with Diabetes
DownloadFall 2012
While guidelines for seasonal influenza vaccinations single out working age (< 65) adults with diabetes, vaccination rates in this group remain below national targets. Historically, there has been limited evidence to support these guidelines. This dissertation comprises four studies investigating...
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Fall 2014
Evidence-based medicine (EBM) is, simply, the conscientious and judicious use of medical research (“evidence”) in clinical practice (Sackett et al. 2000:1). EBM emerged as a solution to various identified uncertainties in clinical practice as a programme for intervention at the level of...
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2012
Barnard, D., Norton, P. G., Batra-Garga, N., Cummings, G. G., Estabrooks C. A., Cranley, L. A.
Background: In Canada, healthcare aides (also referred to as nurse aides, personal support workers, nursing assistants) are unregulated personnel who provide 70-80% of direct care to residents living in nursing homes. Although they are an integral part of the care team their contributions to the...
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Influenza Vaccination in Patients with Diabetes: Exploration of the Healthy User in Pharmacoepidemiology Studies
DownloadFall 2015
Pharmacoepidemiologic studies of preventive medications or therapies are prone to the healthy user bias, as patients who are prescribed and adhere to preventive medications/therapies are likely different than patients not receiving these medications in multiple aspects of their lives. These...
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Spring 2013
Immunogenicity of intramuscular influenza vaccine is suboptimal in organ transplant recipients although intradermal vaccine may be superior by targeting dermal dendritic cells to stimulate a response. 229 patients were randomized to IM or high-dose ID vaccine during the 2010-11 season. Pre- and...
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Spring 2010
These two studies investigate the immune responses of lung and kidney transplant recipients to the influenza vaccine. The study involving kidney transplant recipients developed a novel flow cytometry assay to measure cell-mediated immunity in response to influenza vaccination. The activation of...
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2011
Gagnon, M.P., Grimshaw, J., Legare, F., Labarthe, J., Roch, R., Estabrooks, C.A., Ghandour, E.K., Ouimet, M.
Background: Knowledge translation (KT) is an imperative in order to implement research-based and contextualized practices that can answer the numerous challenges of complex health problems. The Chronic Care Model (CCM) provides a conceptual framework to guide the implementation process in chronic...
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2007
Lake, R., Bailey, T., Yonge, O., Marrie, T.J., Herman, B., Rosychuk, R.J.
To assess knowledge of pandemic influenza, we administered a questionnaire to all medical students at the University of Alberta; 354 (69%) of 510 students responded. Data from questionnaires such as this could help determine the role of medical students during a public health emergency.
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Partners in Research: Building Academic-Practice Partnerships to Educate and Mentor Advanced Practice Nurses
Download2016-11-01
McKinlay, James, Valaitis, Ruta, Sherifali, Diana, Donald, Faith, Bryant-Lukosius, Denise, Carter, Nancy, Covell, Christine L., Tranmer, Joan, Kilpatrick, Kelley, Harbman, Patricia, Rawson, Krista, Gibbins, Sharyn, Martin-Misener, Ruth
Rationale: Clinical practice is the primary focus of advanced practice nursing (APN) roles. However, with unprecedented needs for healthcare reform and quality improvement (QI), healthcare administrators are seeking new ways to utilize all dimensions of APN expertise, especially related to...