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Skip to Search Results- 2Curtis, Jonathan M.
- 2Field, Catherine J.
- 2Jacobs, Rene L.
- 1Bell, Rhonda C.
- 1Cao, Guoqing
- 1Chan, Catherine B.
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2015
Field, Catherine J., Lewis, Erin, Curtis, Jonathan M., Richard, Caroline, Goruk, Susan, Jacobs, Rene L., Ruth, Megan R., Dellschaft, Neele S.
Choline demands during lactation are high; however, detailed knowledge is lacking regarding the optimal dietary intake during this critical period. The present study was designed to determine the effects of varying intakes of choline on maternal immune function during lactation. Primiparous...
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Estimation of choline intake from 24 h dietary intake recalls and contribution of egg and milk consumption to intake among pregnant and lactating women in Alberta
Download2014
Jacobs, Rene L., Field, Catherine J., Subhan, Fatheema B., Bell, Rhonda C., Lewis, Erin D., McCargar, Linda J., Curtis, Jonathan M.
Despite recommendations for higher choline intakes during pregnancy and lactation, there is limited research regarding maternal intake during these important periods. In the present study, we estimated dietary choline intake during pregnancy and lactation in a population of Albertan women and the...
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2012
Wan, Zhongxiao, MacDonald, Tara, Wright, David C., Holloway, Graham P., Chan, Catherine B., Perry, Christopher G.
Background Adipose tissue mitochondria have been implicated as key mediators of systemic metabolism. We have shown that IL-6 activates AMPK, a mediator of mitochondrial biogenesis, in adipose tissue; however, IL-6−/− mice fed a high fat diet have been reported to develop insulin resistance. These...
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Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity
Download2010
Kuo, Ming-Shang, Dyck, Jason R. B., Sletten, Torunn, Proctor, Spencer D., Jacobs, René L., Lingrell, Susanne, Cao, Guoqing, Peake, David A., Kennedy, Brian P., Zhao, Yang, Vance, Dennis E., Koonen, Debby P. Y., Su, Brian
Phosphatidylcholine (PC) is synthesized from choline via the CDP-choline pathway. Liver cells can also synthesize PC via the sequential methylation of phosphatidylethanolamine, catalyzed by phosphatidylethanolamine N-methyltransferase (PEMT). The current study investigates whether or not hepatic...