Search
Skip to Search Results- 19Graduate and Postdoctoral Studies (GPS), Faculty of
- 19Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 6Agricultural, Food and Nutritional Science, Department of
- 6Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 3Biological Sciences, Department of
- 3Biological Sciences, Department of/Journal Articles (Biological Sciences)
-
Culture and Characterization of Kefir Organisms to Reproduce the Health Benefits of Traditional Kefir
DownloadSpring 2020
Fermented dairy products such as kefir have long been associated with a host of health benefits; however, the role that microbial composition has in these benefits has not been properly examined. This research aimed to examine how kefir impacts host metabolic health, as well as how alterations to...
-
Dietary oxysterols are incorporated in plasma triglyceride rich lipoproteins, increase their susceptibility to oxidation and increase aortic cholesterol concentration of rabbits
Download1998
Mamo, John C. L., Croft, Kevin D., Vine, Donna F., Mori, Tetsuya, Beilin, Lawrence J.
Early fatty streaks and advanced lesions are characterized by the deposition of cholesterol and cholesterol oxidation products (oxysterols). Oxysterols have been shown to be cytotoxic and pro-atherogenic compared to cholesterol and are found in cholesterol-rich processed foods. The consumption of...
-
Spring 2015
Cholesterol is well known for its adverse cardiovascular effects, however it has crucial cellular roles. For instance, cholesterol is a key component of eukaryotic cell membranes and constitutes the principle steroid hormone precursor in most animals. Cellular cholesterol concentrations have to...
-
Effect of Cholesterol Accumulation on the Metabolism of Amyloid Precursor Protein (APP) in Cultured N2a Cells
DownloadFall 2015
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder believed to be triggered by the accumulation of β-amyloid (Aβ) peptides derived from the proteolytic processing of amyloid precursor protein (APP). Accumulated evidence has shown that alterations in the levels and/or subcellular...
-
Exploring Novel Therapies for Motor and Non-Motor Symptoms in a Mouse Model of Multiple Sclerosis
DownloadSpring 2016
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system characterized by neurodegeneration, inflammation and demyelination. Symptoms of multiple sclerosis not only include motor deficits, but also secondary symptoms of pain, depression and anxiety. The purpose of...
-
2001
Bohnert, H. J., Deyholos, M., Brazille, S., Wang, H., Kawai, K., Borchert, C., Galbraith, D., Kawasaki, S.
Transcript regulation in response to high salinity was investigated for salt-tolerant rice (var Pokkali) with microarrays including 1728 cDNAs from libraries of salt-stressed roots. NaCl at 150 mM reduced photosynthesis to one tenth of the prestress value within minutes. Hybridizations of RNA to...
-
Glial Expression of Amyloid Precursor Protein (APP) and its Processing Enzymes in the ANPC Mouse Model
DownloadFall 2021
Alzheimer’s disease (AD) is a complex and progressive neurodegenerative disorder believed to be triggered by the accumulation of β-amyloid (Aβ) peptides derived from the proteolytic processing of amyloid precursor protein (APP). The regions primarily affected in AD brains are the hippocampus and...
-
2007
Seligmann, B., Deyholos, M., Kris, R. M., Felder, S., Botros, I., Galbraith, D. W., Martel, R., Hinton, J., Lambert, G. M.
High-throughput gene expression analysis of genes expressed during salt stress was performed using a novel multiplexed quantitative nuclease protection assay that involves customized DNA microarrays printed within the individual wells of 96-well plates. The levels of expression of the transcripts...
-
Increased hypolipidemic benefits of cis-9, trans-11 conjugated linoleic acid in combination with trans-11 vaccenic acid in a rodent model of the metabolic syndrome, the JCR:LA-cp rat
Download2010
Proctor, Spencer D., Lu, Jing, Shen, Jianheng, Reaney, Martin J., Wright, David C., Vine, Donna F., Jacome-Sosa, M. Miriam, Field, Catherine J., Wang, Ye, Ruth, Megan R.
Background Conjugated linoleic acid (cis-9, trans-11 CLA) and trans-11 vaccenic acid (VA) are found naturally in ruminant-derived foods. CLA has been shown to have numerous potential health related effects and has been extensively investigated. More recently, we have shown that VA has...