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Targeted Application of Dietary Fibers for Selective Modulation of the Gut Microbiota and Improved Human Health
DownloadFall 2020
Obesity and associated comorbidities have reached epidemic proportions worldwide. Observational studies provide consistent evidence that plant-based diets rich in dietary fibers (DFs) reduce chronic disease risk. Mechanistic studies have established processes by which DFs improve health, with one...
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Traditional kefir reduces weight gain and improves plasma and liver lipid profiles more successfully than a commercial equivalent in a mouse model of obesity
Download2018-07-01
Bourrie, Benjamin C.T., Cotter, Paul D., Willing, Ben P.
Kefir, a fermented milk beverage, has shown promise in alleviating obesity and associated metabolic dysfunction. However, microbial characteristics are variable among traditional kefirs, and commercial kefirs drastically differ from traditional kefir. This study investigated the ability of four...
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Updating Local Birth Weight Percentiles and Statistical Methods Motivated by Challenges in Analysis of Microbiome Studies
DownloadFall 2022
This dissertation contains two main parts. In part one, I updated the current reference for sex-specific birth weight percentiles by gestational age, overall, and for specific ethnic groups, based on data from all singleton live-birth deliveries from 2005 to 2014 in Alberta, Canada. Crude and...
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Xylo-oligosaccharides and virginiamycin differentially modulate gut microbial composition in chickens
Download2015
Zhao, Xin, Pourabedin, Mohsen, Guan, Leluo
Background The emergence and spread of antibiotic resistance in pathogens have led to a restriction on the use of antibiotic growth promoters (AGPs) in animal feed in some countries. The potential negative after-effects of a ban on AGPs could be mitigated by improving animal intestinal health...