Search
Skip to Search Results- 1Abbasi Dezfouli, Meysam
- 1Almasud,Alaa A
- 1Ayoub, Ahmed T
- 1Batycky, Anya
- 1Bekele, Raie Taye
- 1Crisp, Nicole
- 3Department of Biochemistry
- 3Department of Civil and Environmental Engineering
- 3Faculty of Nursing
- 2Department of Agricultural, Food, and Nutritional Science
- 2Department of Biological Sciences
- 2Faculty of Pharmacy and Pharmaceutical Sciences
- 2Goss, Greg (Biological Sciences)
- 1Baracos, Vickie (Oncology, Agricultural, Food, and Nutritional Science)
- 1Brindley, David N. (University of Alberta, Biochemistry)
- 1Dr Vera Mazurak, Agricultural, Food and Nutritional Science
- 1Dr. Afsaneh Lavasanifar (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Dr. Andrew Belch (Department of Oncology, Faculty of Medicine and Dentistry)
-
Modulation of the uptake and toxicity of PFOA by Polystyrene and Titanium dioxide nanoparticles in Pacific oysters (Magallana gigas) and Daphnia (Daphnia magna)
DownloadFall 2023
Nanomaterial toxicity is a major concern in today’s world. The benefits of nanoparticle use have led to the production of various kinds of nanomaterials including a high volume of nanoplastics, TiO2 nanoparticles, and CeO nanoparticles. Different nanomaterials are shown to be a suitable vector...
-
Nanodelivery of Novel Inhibitors of ERCC1/XPF for sensitizing colorectal cancer cell to platinum drugs
DownloadSpring 2023
This project's long-term goal is to increase the efficacy of genotoxic therapeutics through thesensitization of cells to DNA-damaging therapy ahead of the treatment. The focus of this projectwas on the enhancement of platinum-based chemotherapeutics in colorectal cancer usingcolorectal cancer...
-
Non digestible carbohydrates in the diet determine toxicity of irinotecan (CPT-11)/5-fluorouracil in rats independently of β-glucuronidase activity in intestinal lumen
DownloadFall 2012
Aim of this study was to assess effects of non-digestible carbohydrates on the pathobiology of mucosal injury after chemotherapy. Rats bearing colon tumor (n=6/diet) were fed diets including 8% (w/w) as either cellulose, inulin, fructo-oligosaccharide (OligoF), 50:50 (w/w) inulin and oligoF...
-
Spring 2011
To ensure oil sands process water (OSPW) is suitable for discharge into the environment, advanced water treatment technologies are required. In this study, integrated ozonation-biodegradation was investigated as a potential treatment option for OSPW. The treatment efficiency was evaluated in...
-
Quantitative Label-Free Comparative Proteomic Analyses of Eukaryotic Tissues via Mass Spectrometry
DownloadFall 2018
In recent years, rapid advances in genomic and transcriptomic sequencing technologies have enabled the compilation of vast libraries of protein sequences and thus an explosion in bioinformatics-based fields of research. Among these is proteomics – the study of global protein abundance within a...
-
Fall 2019
Breast cancer is the leading cause of death among women worldwide. Fortunately, death rates have been declining since 1990, due to the increase in early detection, testing, and improved treatment. However, despite the advancement of targeted and hormone therapies for certain molecular sub-types...
-
The evaluation of toxic effects induced by exposure of mammals to oil sands process-affected water and its organic fraction
DownloadSpring 2018
Oil sands process-affected water (OSPW) produced by the surface-mining oil sands industry in Alberta, has been shown to be toxic to a variety of organisms. Much of this toxicity has been attributed to the dissolved organic compounds, primarily naphthenic acids (NAs). Under a no-release practice,...
-
Spring 2016
Tamoxifen is the accepted therapy for patients with estrogen receptor α (ERα)−positive breast cancer. However, clinical resistance to tamoxifen, as demonstrated by recurrence or progression on therapy, is frequent and precedes death from metastases. To improve breast cancer treatment it is vital...
-
Uptake of waterborne selenite, and its toxic effects, in the water flea (Daphnia magna), Westslope cutthroat trout (Oncorhynchus clarkii lewisi) and rainbow trout (Oncorhynchus mykiss)
DownloadSpring 2024
Selenium is an essential element, playing an important role in many physiological processes. However, it possesses a narrow margin between essentiality and toxicity. In aquatic systems, selenium is increasingly identified as a trace element of major concern with levels exceeding regulatory...