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Skip to Search Results- 25Graduate and Postdoctoral Studies (GPS), Faculty of
- 25Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 5Biological Sciences, Department of
- 3Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 2Agricultural, Food and Nutritional Science, Department of
- 2Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 6Department of Biological Sciences
- 3Department of Agricultural, Food, and Nutritional Science
- 3Department of Biochemistry
- 3Faculty of Nursing
- 2Department of Renewable Resources
- 2Faculty of Pharmacy and Pharmaceutical Sciences
- 5Goss, Greg (Biological Sciences)
- 1Alessi, Daniel (Earth and Atmospheric Sciences)
- 1Baracos, Vickie (Oncology, Agricultural, Food, and Nutritional Science)
- 1Brindley, David N. (University of Alberta, Biochemistry)
- 1Clugston, Robin (Physiology)
- 1Dr Vera Mazurak, Agricultural, Food and Nutritional Science
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A Novel Comparative Analysis Approach to Personalize Chemotherapy Dose Calculation in Early Breast Cancer
DownloadFall 2018
Background Worldwide, body surface area [BSA] is used to calculate chemotherapy dose. The BSA formula was originally developed in 1916, derived from height and weight, with no consideration of other patient characteristics. Most chemotherapy agents have a narrow therapeutic index and are...
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Fall 2011
This study determined how chemotherapy treatment for colorectal cancer alters hepatic fat metabolism. Livers were isolated from tumor-bearing animals after one and two cycles of chemotherapy consisting of irinotecan plus 5-fluorouracil. Fatty acid amounts and composition within triglycerides (TG)...
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Fall 2010
Escalating cancer rates and an increase in the complexity and duration of chemotherapy regimens have brought the issue of cancer treatment at home to the forefront. For the participants of this study, home chemotherapy was offered as a potential treatment choice. Ten patients who accepted were...
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Fall 2016
The increasing anthropogenic pressure on biodiversity in the tropics is resulting in changes to ecosystem structure and increasing species extinction rates (Collen et al. 2013). These issues are heightened in the tropics where 50% of the world’s biodiversity is held in 7% of the world’s...
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Cognitive Dysfunction in non-Hodgkin's Lymphoma Patients Treated with Front-Line Chemotherapy
DownloadSpring 2015
Despite the research to date, the characteristics and impact of cognitive dysfunction (CD) in cancer patients following chemotherapy is still not well understood. It is estimated approximately 20% of patients will manifest measurable cognitive deficits on neuropsychological testing...
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Fall 2015
Microtubules are cellular structures that are crucial to many cellular functions including maintenance of cell shape, vesicular transport, and cell division. The dynamic instability of microtubules is the basic feature which enables them to do their cellular functions. Their pivotal role in cell...
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Development of polymer and lipid based nano-delivery systems for targeted cancer chemotherapy
DownloadFall 2012
Conventional chemotherapy agents can kill tumor cells and inhibit tumor growth, but they produce severe side effects on normal cells at the same time. To shift the balance towards tumoral effects, it would be desirable to direct the anti-cancer drug towards tumor while restricting drug access to...
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Differential exudation of polypeptides by roots of aluminum-resistant and aluminum-sensitive cultivars of Triticum aestivum L. in response to aluminum stress
Download1994
Basu, A., Taylor, G. J., Basu, U.
Cultivars of Triticum aestivum differing in resistance to Al were grown under aseptic conditions in the presence and absence of Al and polypeptides present in root exudates were collected, concentrated, and analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Upon exposure to...
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Eicosapentaenoic and Docosahexaenoic Fatty Acids Modify Skeletal Muscle Fat Infiltration in an Animal Model of Colorectal Cancer Receiving Chemotherapy
DownloadSpring 2017
Background: Myosteatosis is defined as low skeletal muscle radio-density with elevated amounts of intermuscular adipose tissue, assessed using computed tomography. Myosteatosis has been recently observed to be associated with mortality in people with cancer. Previous work from our lab reported...
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Fall 2012
In this study, growth of seven hybrid poplar clones and one pure poplar clone was investigated in relation to leaf, shoot, and root physiology under field conditions. Clones included: Walker (24 - P. deltoides x P. xpetrowskyana), Assiniboine (25 - open pollinated Walker cv. Assiniboine),...