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Skip to Search Results- 1Abbasi Dezfouli, Meysam
- 1Almasud,Alaa A
- 1Ayoub, Ahmed T
- 1Bekele, Raie Taye
- 1Blunt, Brian
- 1Crisp, Nicole
- 9Department of Biological Sciences
- 3Department of Biochemistry
- 3Faculty of Nursing
- 2Department of Agricultural, Food, and Nutritional Science
- 2Department of Civil and Environmental Engineering
- 2Faculty of Pharmacy and Pharmaceutical Sciences
- 3Goss, Greg (Biological Sciences)
- 1Adamowicz, Vic (Resource Economics and Environmental Sociology)
- 1Alessi, Daniel (Earth and Atmospheric Sciences)
- 1Baracos, Vickie (Oncology, Agricultural, Food, and Nutritional Science)
- 1Barreda, Daniel (Biological Sciences)
- 1Belosevic, Miodrag (Biological Sciences)
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A Novel Comparative Analysis Approach to Personalize Chemotherapy Dose Calculation in Early Breast Cancer
DownloadFall 2018
Background Worldwide, body surface area [BSA] is used to calculate chemotherapy dose. The BSA formula was originally developed in 1916, derived from height and weight, with no consideration of other patient characteristics. Most chemotherapy agents have a narrow therapeutic index and are...
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Fall 2011
This study determined how chemotherapy treatment for colorectal cancer alters hepatic fat metabolism. Livers were isolated from tumor-bearing animals after one and two cycles of chemotherapy consisting of irinotecan plus 5-fluorouracil. Fatty acid amounts and composition within triglycerides (TG)...
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Fall 2009
I investigated cellular mechanisms of ion and acid-base transport in rainbow trout (Oncorhyncus mykiss), crabs (Neohelice granulata), zebrafish (Danio rerio), Pacific hagfish (Eptatretus stoutii), and mosquito larvae (Aedes aegypti) with a primary focus on discerning the mechanisms governing ion...
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Fall 2010
Escalating cancer rates and an increase in the complexity and duration of chemotherapy regimens have brought the issue of cancer treatment at home to the forefront. For the participants of this study, home chemotherapy was offered as a potential treatment choice. Ten patients who accepted were...
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Cognitive Dysfunction in non-Hodgkin's Lymphoma Patients Treated with Front-Line Chemotherapy
DownloadSpring 2015
Despite the research to date, the characteristics and impact of cognitive dysfunction (CD) in cancer patients following chemotherapy is still not well understood. It is estimated approximately 20% of patients will manifest measurable cognitive deficits on neuropsychological testing...
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Fall 2015
Microtubules are cellular structures that are crucial to many cellular functions including maintenance of cell shape, vesicular transport, and cell division. The dynamic instability of microtubules is the basic feature which enables them to do their cellular functions. Their pivotal role in cell...
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Development of polymer and lipid based nano-delivery systems for targeted cancer chemotherapy
DownloadFall 2012
Conventional chemotherapy agents can kill tumor cells and inhibit tumor growth, but they produce severe side effects on normal cells at the same time. To shift the balance towards tumoral effects, it would be desirable to direct the anti-cancer drug towards tumor while restricting drug access to...
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Spring 2012
Decades of fish introductions into mountain lakes have altered invertebrate communities. I assessed the current status of fish populations and their effects on crustacean zooplankton communities by sampling 37 lakes in the mountain parks, where stocking practices had been halted over 25 years...
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Fall 2020
Early life exposure to stress can have life-long effects on an organism. These effects may be detrimental, or they may be adaptive if they allow the organism to develop an adult phenotype which better matches the environment predicted by the stressor. Early life stress influences many traits,...
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Eicosapentaenoic and Docosahexaenoic Fatty Acids Modify Skeletal Muscle Fat Infiltration in an Animal Model of Colorectal Cancer Receiving Chemotherapy
DownloadSpring 2017
Background: Myosteatosis is defined as low skeletal muscle radio-density with elevated amounts of intermuscular adipose tissue, assessed using computed tomography. Myosteatosis has been recently observed to be associated with mortality in people with cancer. Previous work from our lab reported...