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2007

Gerdts, Volker, Meurens, Francois, Willing, Benjamin P., Berri, Mustapha, Siggers, Richard H., Van Kessel, Andrew G., Salmon, Henri

Background CCL25/TECK and CCL28/MEC are CC chemokines primarily expressed in thymic dendritic cells and mucosal epithelial cells. Their receptors, CCR9 and CCR10, are mainly expressed on T and B lymphocytes. In human, mouse, pig and sheep CCL25 and CCL28 play an important role in the segregation...

2016-03-09

McAllister, Tim A., Wang, Ou, Plastow, Graham, Stanford, Kim, Liang, Guanxiang, Guan, Le L., Selinger, Brent

Super-shedder cattle are a major disseminator of E. coli O157:H7 into the environment, and the terminal rectum has been proposed as the primary E. coli O157:H7 colonization site. This study aimed to identify host factors that are associated with the super-shedding process by comparing...

Spring 2014

Vaisipour, Saman

Gene expression microarrays are widely used to better understand the complex biological mechanisms inside cells. One of the main obstacles of applying statistical learning algorithms to microarray data is the large gap between the number of features (p) and the number of available instances (n),...

2016

Ladinig, Andrea, Stothard, Paul, Wilkinson, Jamie M., Kommadath, Arun, Plastow, Graham S., Harding, John C. S., Bao, Hua, Lunney, Joan K.

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnant females causes fetal death and increased piglet mortality, but there is substantial variation in the extent of reproductive pathology between individual dams. This study used RNA-sequencing to characterize the whole...

2014

Basu, Urmila, Verma, Shiv, Rahman, Muhammad H., Deyholos, Michael K., Kav, Nat N. V.

Canola (oilseed rape, Brassica napus L.) is susceptible to infection by the biotrophic protist Plasmodiophora brassicae, the causal agent of clubroot. To understand the roles of microRNAs (miRNAs) during the post-transcriptional regulation of disease initiation and progression, we have...

2013-01-01

Bohlmann, Jörg, Bonnett, Tiffany R., Pitt, Caitlin, Keeling, Christopher I., Yuen, Macaire M. S., Huber, Dezene P. W., Robert, Jeanne A.

The mountain pine beetle, Dendroctonus ponderosae, is a native species of bark beetle (Coleoptera: Curculionidae) that caused unprecedented damage to the pine forests of British Columbia and other parts of western North America and is currently expanding its range into the boreal forests of...

Spring 2015

Bentley, Pamela AP

Photoperiod, or day length, generates a highly accurate biological calendar that allows animals to anticipate and adapt to environmental change throughout the year. Photoperiod coordinates both daily and yearly rhythms associated with sleep/wake cycles, behavior, and reproduction, including...

2013-01-01

Thiesen, Aducio, Rioux, Kevin P., Tso, Robert, Kish, Lisa, Barkema, Herman W., Madsen, Karen L., Vincent, Renaud, Wine, Eytan, Kaplan, Gilaad G., Hotte, Naomi, Gänzle, Michael G.

Background Particulate matter (PM) is a key pollutant in ambient air that has been associated with negative health conditions in urban environments. The aim of this study was to examine the effects of orally administered PM on the gut microbiome and immune function under normal and inflammatory...

Fall 2012

Schlau, Nicole A

Sub-acute ruminal acidosis is a digestive disorder experienced by animals fed a high grain diet, and causes substantial economic loss to the dairy industry. The objective of this research was to evaluate novel approaches to manage and prevent sub-acute ruminal acidosis. In Study 1, I found that...

Spring 2014

Kelly, Karen

Mandatory folate fortification polices in North America have resulted in high levels of circulating folate in the population. At the same time, a trend toward increased energy intake and reduced energy expenditure has lead to an increased prevalence of obesity, characterized by an accumulation of...