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Skip to Search Results- 25Graduate and Postdoctoral Studies (GPS), Faculty of
- 25Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 4Roy Berg Kinsella Research Ranch
- 4Roy Berg Kinsella Research Ranch/Journal Articles (Kinsella Ranch)
- 2Agricultural, Food and Nutritional Science, Department of
- 2Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 6Department of Agricultural, Food, and Nutritional Science
- 3Department of Pharmacology
- 2Department of Medicine
- 2Department of Oncology
- 2Department of Physiology
- 1Department of Food Science
- 1Ambrose, Divakar (Department of Agricultural, Food and Nutritional Science)
- 1Baker, Kristi (Oncology)
- 1Bressler, David C. (Agricultural, Food and Nutritional Science)
- 1Davidge, Sandra T. (Physiology/Obstetrics and Gynecology)
- 1Dyck, Jason RB (Pediatrics)/ McAlister, Finlay A (Medicine)
- 1Febbraio,Maria (Dentistry)
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A Novel Comparative Analysis Approach to Personalize Chemotherapy Dose Calculation in Early Breast Cancer
DownloadFall 2018
Background Worldwide, body surface area [BSA] is used to calculate chemotherapy dose. The BSA formula was originally developed in 1916, derived from height and weight, with no consideration of other patient characteristics. Most chemotherapy agents have a narrow therapeutic index and are...
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Antimicrobial activity in the egg wax of the tick Amblyomma hebraeum (Acari: Ixodidae) is associated with free fatty acids C16:1 and C18:2
Download2012
Yu, Z., Liu, J., Kaufman, W. R., Thomson, E. L. S., Dennis, J. J., Jacobs, R. L.
Abstract: Untreated eggs of the tick Amblyomma hebraeum Koch (Acari: Ixodidae) exhibited antimicrobial activity (AMA) against Gram-negative but not Gram-positive bacteria; eggs denuded of wax by solvent extraction showed no AMA. The unfractionated egg wax extract, however, showed AMA against...
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Brain fatty acid-binding protein and ω-3/ω-6 fatty acids: Mechanistic insight into the poor prognosis of malignant glioma cell migration
Download2010
Godbout, Roseline, Mita, Raja, Field, Catherine J., Beaulieu, Michael J.
Malignant gliomas (MG) are highly infiltrative tumors that consistently recur despite aggressive treatment. Brain fatty acid-binding protein (FABP7), which binds docosahexaenoic acid (DHA) and arachidonic acid (AA), localizes to sites of tumor infiltration and is associated with a poor prognosis...
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Cardioprotective Properties of a Synthetic, Structurally Mimetic 19,20- Epoxydocosapentaenoic Acid Analog: Implications of SIRT3 Potentiation on Ischemia Reperfusion Injury
DownloadFall 2024
Mounting evidence suggests that CYP epoxygenase-derived metabolites of docosahexaenoic acid, called epoxydocosapentaenoic acids (EDPs), limit mitochondrial damage following cardiac injury. In particular, the 19,20-EDP regioisomer has demonstrated potent cardioprotective action. Thus, we...
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Composition and correlation studies of fatty acids in seed oil of yellow sarson (Brassica campestris L.) cultivars and backcross derived zero erucic acid yellow sarson populations
Download1999-01-01
Rahman, M. H., Stølen, O., Rahman, L., Rahman, M. M.
The Yellow Sarson (Brassica campestris) cultivars of Bangladesh origin contain a high level (54%) of erucic fatty acid (C22:1). In the seeds of backcross derived zero-erucic acid Yellow Sarson populations, absence of erucic acid caused a simultaneous reduction in the content of arachidic (C20:0),...
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Design and synthesis of renewable lipid-based nanocarriers with thermosensitivity for targeted drug delivery applications
DownloadSpring 2024
Numerous drug molecules currently available on the market suffer from short half-life, in vivo instability, poor bioavailability, rapid degradation and inappropriate distribution. While nanocarriers have emerged as a promising solution to address these issues, the primary objective and challenge...
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Fall 2016
Multiple sources suggest that insulin resistance and derangements of cardiac metabolism are among the earliest signs of type-2 diabetes detected in the heart. Unfortunately, limited evidence reflects early changes in cardiac mitochondrial metabolism linked to the development of this disease....