Search
Skip to Search Results- 2Berry, Tanya R
- 2Veldhoen, Richard
- 1Aburahess, Salah
- 1Akuamoah Boateng, Maxwell
- 1Alberta Centre for Active Living
- 1Alqahtani,Hind M
- 32Graduate and Postdoctoral Studies (GPS), Faculty of
- 32Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 3Kinesiology, Sport, and Recreation, Faculty of
- 2Agricultural, Food and Nutritional Science, Department of
- 2Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Kinesiology, Sport, and Recreation, Faculty of/Research Data and Materials (Kinesiology, Sport, and Recreation)
-
Fall 2015
Tumor targeting ligands provide a promising solution to the problems associated with the selective delivery of conventional cancer chemotherapeutics and diagnostics to cancer cells. Therefore, numerous cancer cell surface targeting peptides have been identified and evaluated. These peptides have...
-
Establishing the anti-cancer effects of unsaturated fatty acids and a novel oil on human breast cancer cells
DownloadFall 2012
N-3 and n-6 fatty acids and conjugated linoleic (CLA) acid have been known to inhibit breast cancer cell growth, however, effects on normal cells and of single and mixtures of n-3 and n-6 pathway intermediates have not been thoroughly investigated. The objective of this thesis was to determine...
-
Fall 2021
Breast cancer is the most common cancer amongst women in Canada. The current treatment regime for early stage breast cancers is breast-conserving surgery with radiation therapy. However, 10-20% of patients develop local recurrence, and some exhibit metastatic spread, which is associated with a...
-
Fall 2015
Background: Breast conserving surgery (BCS) followed by radiation is the preferred treatment option for early stage breast cancer because it is less invasive than the alternative treatment, mastectomy, and provides a better cosmetic outcome and a superior quality of life. Positive surgical...
-
Fall 2010
Breast cancer is the most common cancer and the leading cause of cancer-related death among Canadian women. Despite improvements in treatment and early detection, there is still a need to develop novel therapies for breast cancer management. Aberrant Notch signaling is tumorigenic and is...
-
Fall 2013
Breast cancer is the most common cancer among women in the developed world. The disease results from the combined effects of genetic, environmental, reproductive and lifestyle risk factors. Germline DNA variations identified thus far by linkage and genome-wide association studies (GWASs) account...
-
Fall 2014
Evidence-based medicine (EBM) is, simply, the conscientious and judicious use of medical research (“evidence”) in clinical practice (Sackett et al. 2000:1). EBM emerged as a solution to various identified uncertainties in clinical practice as a programme for intervention at the level of...
-
Fall 2023
Angiogenesis, the process of forming new blood vessels from a pre-exciting vasculature, is an essential component of embryonic development, tissue remodelling, wound healing, and tumor growth. This process is strictly regulated by a vast array of cellular signalling pathways involving kinases,...
-
Spring 2021
Vaccinia virus (VACV) has shown promise as an oncolytic agent for treating a variety of tumour types, with preliminary results suggesting that this strategy holds promise for treating breast cancer. Our lab has previously modified VACV by deleting virally-encoded enzymes responsible for dNTP...
-
Increased estrogen receptor expression leads to a novel DNA binding signature which differentiates luminal A and luminal B breast cancers
DownloadFall 2018
Eighty percent of all breast cancers are estrogen receptor positive (ER+) and molecular profiling has identified two ER+ subtypes: luminal A and luminal B. The accurate diagnosis of these luminal subtypes is one of the greatest clinical challenges with current gene assays obtaining only 75%...