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Skip to Search Results- 2Berry, Tanya R
- 2Veldhoen, Richard
- 1Aburahess, Salah
- 1Akuamoah Boateng, Maxwell
- 1Alberta Centre for Active Living
- 1Alqahtani,Hind M
- 32Graduate and Postdoctoral Studies (GPS), Faculty of
- 32Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 3Kinesiology, Sport, and Recreation, Faculty of
- 2Agricultural, Food and Nutritional Science, Department of
- 2Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Kinesiology, Sport, and Recreation, Faculty of/Research Data and Materials (Kinesiology, Sport, and Recreation)
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Anti-Cancer Mechanism of Trastuzumab via Blocking Nuclear HER2 Function and Epigenetic Mechanism of Resistance
DownloadSpring 2020
HER2 receptor tyrosine kinase (encoded by ERBB2 gene) is overexpressed in approximately 25% of all breast cancer tumors (known as HER2-positive breast cancers). Overexpression of HER2 causes overactivation of downstream receptor tyrosine kinase pathways including PI3K/Akt and MAPK pathways and is...
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Antioxidant responses in harvested leaves of two cultivars of spinach differing in senescence rates
Download2001-01-01
Hodges, D. Mark, Forney, Charles F., Wismer, Wendy V.
The objective of this study was to assess responses of certain antioxidants in harvested leaves of selected cultivars of spinach (Spinacia oleracea L.) differing in postharvest senescence rates in order to explore the significance of these antioxidants in postharvest senescence regulation and...
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Association mapping of genes using whole genome polymorphism arrays: Identification of markers of breast cancer susceptibility in Alberta women
DownloadFall 2010
Chakravarthy Sridharan, Malinee
Breast cancer is a heterogeneous, polygenic disease and is influenced by genetic, environmental and life-style factors. Many single nucleotide polymorphisms (SNPs) associated with breast cancer risk have been identified in genome-wide association studies (GWASs) by several research groups for...
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Spring 2015
Autotaxin is a secreted enzyme that produces most of the extracellular lysophosphatidate from lysophosphatidylcholine, the most abundant phospholipid in plasma. Lysophosphatidate mediates many physiological and pathological processes by signaling through six G-protein-coupled receptors to promote...
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Spring 2012
This dissertation explores breast cancer experiences by predominately contemporary American women that are creative interventions into, and re-visions of, experiences in medical and therapeutic environs as well as culturally produced post-surgical bodies. During diagnoses, surgeries and...
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Comprehensive transcriptional profiling of NaCl-stressed Arabidopsis roots reveals novel classes of responsive genes
Download2006
Background: Roots are an attractive system for genomic and post-genomic studies of NaCl responses, due to their primary importance to agriculture, and because of their relative structural and biochemical simplicity. Excellent genomic resources have been established for the study of Arabidopsis...
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Fall 2013
Axenfeld-Rieger syndrome (ARS) is a rare developmental disease that affects structures in the anterior segment of the eye. Approximately 50% of ARS patients develop glaucoma, a progressively blinding condition. Although glaucoma is an aging-related disease, ARS patients usually have earlier-onset...
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DDX17 (P72), a Sox2 binding partner, regulates Sox2 to sustain tumorigenic and stem-like properties in a phenotypically distinct subset of estrogen positive breast cancer cells
DownloadSpring 2016
Abstract: Sox2, an embryonic stem cell marker, is involved in the pathogenesis of breast cancer (BC). Sox2 expression is associated with a poor clinical outcome in BC patients. Based on the differential Sox2 transcriptional activity, we have identified the two phenotypically distinct cell...
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Developing an M3 Antagonist for Molecular Imaging of Muscarinic Acetylcholine Receptors in Breast Cancer
DownloadFall 2021
The lack of the three targeted receptors, estrogen, progesterone, and the human epidermal growth factor receptor 2, causes difficulty in treating triple negative type cancers. Most often, patients with this type of malignancy have a low chance of survival. The focus of this work will be on...
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Effect of drying on oxidation of membrane lipids and expression of genes encoded by the Shiga toxin prophage in Escherichia coli
Download2020-01-01
Fang, Yuan, McMullen, Lynn M., Gänzle, Michael G.
Drying processes do not eliminate pathogenic Escherichia coli in foods but induce sublethal injury, which may also induce the Shiga toxin (Stx) prophage. This study investigated the effect of drying on membrane lipid oxidation and stx expression in E. coli. Lipid peroxidation was probed with...