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Skip to Search Results- 8University of Alberta, Department of Biological Sciences
- 6Kitova, Elena N.
- 6Klassen, John S.
- 2Cairo, Christopher W.
- 2Darestani, Reza R.
- 2Eugenio, Luiz
- 27Graduate and Postdoctoral Studies (GPS), Faculty of
- 27Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 17Biological Sciences, Department of
- 9Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 8Biological Sciences, Department of/BioSci OER
- 8Chemistry, Department of
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1995
Abstract: A cluster of genes of the CYP6 family was found in a series of overlapping lambda DASH clones from a genomic library of the house fly, Musca domestica, Four complete genes, CYP6A3, CYP6A4, CYP6A5, and CYP6C1, and fragments of two other genes, CYP6A6 and CYP6C2, were closely linked on a...
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1994
Wright, G.E., Reha-Krantz, L.J., Khan, N.N.
Bacteriophage T4 DNA polymerase was Inhibited by butylphenyl nucleotldes, aphldlcolin and pyrophosphate analogs, but with lower sensitivities than other members of the B family DNA polymerases. The nucleotides N2-{p-n-butylphenyl)dGTP (BuPdGTP) and 2-{p-n-butylanilino)dATP (BuAdATP) inhibited T4...
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Fall 2014
Carbohydrate–protein interactions play key roles in a range of biological processes. Noticeable advancements have been made in understanding the features associated with the recognition of pyranosides (six-membered ring sugars) by proteins. In contrast, similar detailed studies about the...
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Characterisation of novel potential phosphorylation sites in the tumour suppressor Merlin in Drosophila
DownloadFall 2014
Neurofibromatosis Type II is an inherited cancer that manifests as various tumours in the nervous system. Mutations and deletions in the tumour suppressor Merlin (moesin, ezrin, radixin-like protein) are linked to the development of the disease. The mechanism by which Merlin suppresses cell...
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Characterisation of the Non-Canonical Translation Initiation Factor eIF4E-3 as a Merlin Interacting Protein in Drosophila melanogaster
DownloadSpring 2016
Merlin is a tumour suppressor protein, the loss of which is linked to the inherited nervous system tumour syndrome Neurofibromatosis type 2 as well as sporadic tumour development. It is related to the ERM (ezrin-radixin-moesin) protein family, which is involved in linking the cytoskeleton to...
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Fall 2017
Merlin and the ezrin-radixin-moesin (ERM) proteins are key organizers of the cell cortex through linking membrane-associated proteins to the underlying actin cytoskeleton. Merlin and the ERM proteins have been implicated in the maintenance of cell integrity, adhesion, and motility during tissue...
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Characterization of the crosstalk between immunity and metabolism in Drosophila melanogaster model
DownloadFall 2021
Immune and metabolic pathways collectively contribute to the containment of microbial invaders, and persistent activation of immune responses contribute to the development of severe metabolic disorders. To determine how interaction between innate immune system and metabolic responses affected...
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CycA is involved in the control of endoreplication dynamics in the Drosophila bristle lineage
Download2012
Campbell, S.D., Sallé, J., Gho, M., Audibert, A.
Endocycles, which are characterised by repeated rounds of DNA replication without intervening mitosis, are involved in developmental processes associated with an increase in metabolic cell activity and are part of terminal differentiation. Endocycles are currently viewed as a restriction of the...
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Cyclic Adenosine Monophosphate (cAMP) and Fragile X Mental Retardation Protein (FMRP) Mediate Avoidance Behaviour in Drosophila
DownloadFall 2016
Fragile X Syndrome (FXS) is neurodevelopmental disorder caused by a trinucleotide CGG repeat expansion that leads to the methylation and transcriptional silencing of the Fragile X mental retardation 1 (fmr1) gene. This results in the loss of Fragile X mental retardation protein (FMRP), an...