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A high resolution radiation hybrid map of bovine chromosome 14 identifies scaffold rearrangement in the latest bovine assembly
Download2007
Stothard, P., Wang, Z., de Givry, S., Marques, E., Moore, S. S., Womack, J., Murdoch, B.
Background Radiation hybrid (RH) maps are considered to be a tool of choice for fine mapping closely linked loci, considering that the resolution of linkage maps is determined by the number of informative meiosis and recombination events which may require very large mapping populations....
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Arthritis in the Canadian Aboriginal population: north-south differences in prevalence and correlates
Download2010
Ng, Carmina, Chatwood, Susan, Young, T. Kue
"Background: Information on arthritis and other musculoskeletal disorders among Aboriginal people is sparse. Survey data show that arthritis and rheumatism are among the most commonly reported chronic conditions and their prevalence is higher than among non-Aboriginal people. Objective: To...
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Associative plasticity and afferent regulation of corticospinal excitability in uninjured individuals and after incomplete spinal cord injury
DownloadFall 2009
Cortical representations are plastic and are allocated based on the proportional use or disuse of a pathway. A steady stream of sensory input maintains the integrity of cortical networks; while in contrast, alterations in afferent activation promote sensorimotor reorganization. After an...
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1997
Pelletier, Francis J., Elio, Renée
This study examines the problem of belief revision, defined as deciding which of several initially accepted sentences to disbelieve, when new information presents a logical inconsistency with the initial set. In the first three experiments, the initial sentence set included a conditional...
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Beyond the Antibodies: Sera Metabolomic Biomarker Signatures Discriminate Myasthenic And Healthy Cohorts
DownloadFall 2018
Myasthenia Gravis (MG) is a chronic, potentially debilitating autoimmune disease characterized by weakness and rapid fatigue of the voluntary muscles that worsens on exertion and improves on rest. Left untreated, MG symptoms may cause significant morbidity, affecting occupational performance,...
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Chronic Fatigue Mechanisms in Autoimmune Diseases: Lessons from Primary Biliary Cholangitis and Systemic Sclerosis
DownloadFall 2023
Systemic sclerosis (SSc) is an autoimmune disease affecting the body's connective tissues, resulting in progressive fibrosis and vasculopathy. In some cases, individuals with SSc may also develop primary biliary cholangitis (PBC), another autoimmune disease characterized by damage to their...
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2014
Prasad, V., Laouar, L., Jomha, N. M., McGann, L. E., Fahmy, M. D., Almansoori, K. A., Elliott, J. A.
Vitrification of articular cartilage (AC) could enhance tissue availability but requires high concentrations of cyroprotective agents (CPAs). This study investigated relative injuries caused by commonly used CPAs. We hypothesized that the in situ chondrocyte dose–injury relationships of five...
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Spring 2014
Physical activity is recommended in the management of arthritis. This thesis utilized the CCHS 2007-2008 to 1) determine what factors modify physical activity in explaining the likelihood of having arthritis; and 2) what demographic, behavioural and medical factors influence physical activity...
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Fall 2010
Osteoarthritis is characterized by pain and inflammation in joints, typically weight-bearing joints such as the knee. An early warning sign of osteoarthritis is the loss of proteoglycan molecules in the cartilage matrix. A surrogate method for measuring proteoglycan loss is detection of sodium...