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Skip to Search Results- 2Miyashita, Tetsuto
- 1Adams, Emily
- 1Aguirre Monroy, Angelica M
- 1Alam, Kazi, MM
- 1Anderson-Baron, Matthew N
- 1Baleja, James D.
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Modular Design and Directed Evolution for the Development of Genetically Encodable Fluorescent Sensors
DownloadSpring 2019
The development of genetically encodable sensors for optical imaging has revolutionized the way researchers investigate cellular phenomena. Illuminating the molecular dynamics of the cell has become nearly routine with countless improvements in sensor design and directed evolution efforts to...
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Molecular Dynamics Simulations of Polyethylenimine Mediated Nucleic Acid Complexation with Implications for Non-viral Gene Delivery
DownloadSpring 2013
Gene therapy is a promising therapeutic technique that involves delivering nucleic acids into cells. Polycations have evolved into a major category of gene carriers. Polyethylenimine (PEI) is one of the most effective polycationic carriers. Furthermore, modifying PEI with certain lipophilic...
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Spring 2016
Hybrids formed by biological entities and human-made nano-structures have been intensively studied in recent years due to their very interesting properties and applications. DNA-carbon nanotube (CNT) hybrid is one such material and the motivation of this PhD study. The interaction of DNA building...
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Fall 2010
I investigated the paired sternum V glands in thirty-eight trichopteran families and all lepidopteran families possessing the gland or associated structures. Using my morphological data and literature data on sternum V gland secretions, I examined phylogenetic trends in morphology and gland...
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Fall 2013
A basic tenet of comparative studies of the brain is that the larger size of any neural structure is related to the need for progressing more complex or larger quantities of information, the so call Jerison's “principle of proper mass”. Base on this principle, variation of the absolute and...
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Fall 2014
With well over 3,400 described species, snakes undoubtedly represent one of the most successful groups of reptiles. Much has been written about their ecology, behavior, anatomy, relationships and evolution. However, despite the debate about the origin of this taxonomic group dating back to the...
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Fall 2018
A full understanding of the evolution of novel forms requires inference about their origins through the study of variation in extant taxa and clues from the fossil record. However, the origins of morphological diversity in many groups are obscured by the scarcity of transitional fossils or...
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Spring 2019
Organelles serve to compartmentalize biochemical functions within the eukaryotic cell. However, to collectively maintain cellular homeostasis, organelles must communicate in some way in order to coordinate these functions. Two such organelles,the peroxisome and the lipid droplet, are both...
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Fall 2013
The phylogenetic relationships of the destructive spruce budworm group of forest pests (Choristoneura fumiferana species complex) have previously been explored using allozymes, microsatellites, mitochondrial genes and a nuclear gene, but remain poorly resolved with conflicting topologies. I used...
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Fall 2017
Leafrollers moths are one of the most ecologically and economically important groups of herbivorous insects. These Lepidoptera are an ideal model for exploring the drivers that modulate the processes of diversification over time. This thesis analyzes the evolution of Choristoneura Lederer, a well...