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Spring 2020

Griffiths, Cameron

Respiratory syncytial virus (RSV) is a ubiquitous respiratory pathogen that infects almost everyone by the age of two. In high-risk populations, such as infants and elderly individuals, RSV can infect the lower respiratory tract and cause severe symptoms, such as bronchiolitis or pneumonia. As a...

Fall 2009

Magee, Wendy C

The nucleoside phosphonates cidofovir (CDV) and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine [(S)-HPMPA] are analogs of dCMP and dAMP, respectively. Collectively these drugs are effective inhibitors of a wide range of DNA viruses, RNA viruses, and retroviruses. Because they are nucleotide...