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Skip to Search Results- 1Arvanitidis, Anastasia P
- 1Auriat, Angela Michelle
- 1Engin, Elif
- 1McEown, Kristopher
- 1Penner, Mark
- 1Sharma, Arjun V
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Fall 2010
Hyperthermia worsens outcome after ischemia. While it seems reasonable that hyperthermia would also worsen outcome after intracerebral hemorrhage (ICH), clinical studies attempting to find a causative relationship between hyperthermia and outcome have been inconclusive. We induced ICH with an...
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Neurosilence: intracerebral applications of protein synthesis inhibitors eliminate neural activity
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The acquisition of a behavioural response (learning) and the later retrieval of this response (memory) are separated by an endogenous biological process which consolidates the temporary neural changes initiated by training. Intracerebral infusions of stimulants to the hippocampus potentiate this...
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Fall 2015
Despite considerable research progress towards characterizing the neurobiology of anxiety, the focus on putative behavioral markers and the absence of a common behavioural/neurobiological signature for the different classes of anxiolytic drugs have potentially slowed research into the neural...
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Fall 2010
There are two types of stroke: ischemic and hemorrhagic. Intracerebral hemorrhage (ICH) accounts for about 15% of all strokes and is often severe. Currently no treatments are available to reduce injury, but rehabilitation may improve recovery. Most studies focus on ischemia, putting little...
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The Effects of a Western Diet on Stroke Severity and Functional Outcome Following Global Ischemia in Rats
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The present thesis investigated the effects of a western diet (WD) on cell death and functional outcome following global ischemia in rats. Experiment 1 assessed the effects of a 60-day WD regimen on temperature, activity and glucose levels in normal rats. Experiment 2 evaluated the influence of a...
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Fall 2009
Anxiety disorders are the most prevalent of all psychiatric conditions. However, current pharmacological treatments for anxiety disorders are characterized by one or more of the following deficiencies: 1) unwanted side effects, 2) partial efficacy, 3) addictive potential, and 4) delayed onset of...
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The roles of the dorsal and ventral hippocampus in fear and memory of a shock probe experience
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This thesis examined the effects of temporary inactivation of the dorsal or ventral hippocampus on unconditioned and conditioned fear, using the shock-probe test. Rats received either dorsal or ventral hippocampal infusions of Lidocaine, muscimol or saline, before or after exposure to an...