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2019-12-10
Serpe, Michael J., Schirrmacher, Ralf
NFRF Exploration awarded in 2020: Positron Emission Tomography (PET) is among the most sophisticated in vivo imaging modalities using radioactive isotopes that decay by positron emission. PET is non-invasive, painless, and hence patient friendly; provides full-depth images of the human body...
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Novel Insights into the Role of O6-Methylguanine-DNA Methyltransferase in Glioblastoma Angiogenesis, Invasion, and Proliferation
DownloadFall 2012
Glioblastoma multiforme (GBM) is characterized by aberrant angiogenesis, rapid proliferation, and widespread invasion through the brain parenchyma. Thus, the prognosis for these tumors remains extremely poor despite aggressive multimodal treatment including chemotherapy with the alkylating agent...
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Fall 2019
Glioblastoma (GBM), classified as WHO grade IV astrocytoma, is the most common and lethal adult primary brain tumour. Despite recent advances in treatment, GBM prognosis remains largely unchanged with most patients succumbing to the disease within ~15 months of diagnosis. This dismal outcome can...
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Oncology Patients’ Experiences of Using Electronic Patient Portals and Other Online Tools to Support Care and Treatment
DownloadSpring 2022
With the current proliferation of clinical information technologies in Canada, patient portals and other online tools are becoming increasingly adopted in healthcare. Many people use the Internet for health-related purposes to connect with peer support groups and read about their medical...
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Fall 2016
Background: Posttraumatic growth (i.e., positive psychological growth following a traumatic event) is a desired outcome of a cancer diagnosis, however, there is limited research examining interventions to foster experiences of growth. The benefits of physical activity for cancer survivors have...
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Physical Therapy Interventions for Children and Adolescents with Cancer: Collating the Evidence from Research and Clinical Practice
DownloadSpring 2018
Purpose: Children and adolescents with cancer who undergo cancer treatment are at high risk of developing serious late and long-term physical effects, many of which may be amenable to physical therapy (PT). Little is known about the benefits of PT or the services currently provided to address...
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Plasma Membrane Organization and Endocytosis of CD36 in Human Microvascular Endothelial Cells
DownloadSpring 2016
The plasma membrane is a dynamic lipid bilayer that surrounds the cell, embedded with different plasma membrane proteins, aiding communication between the inside and outside of the cells. Its functions are achieved through an intricate organization of lipid-lipid, lipid-protein and...
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2012
Radziwon-Balicka, A., Jurasz, P., Moncada de la Rosa, C.
Platelets, in addition to maintaining hemostasis, also stimulate angiogenesis by generating and releasing, upon activation, factors that promote the growth of new blood vessels. To date, at least 20 angiogenesis-regulating factors have been identified in platelets, including both promoters and...
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Symptoms and quality of life assessment in ambulatory oncology: the evaluation of a clinical assessment tool
DownloadFall 2009
This study addressed gaps in the literature regarding the lack of information about the degree and extent of the relationships among symptom burden, specific symptoms, and health-related quality of life (HRQL). The sample included 89 adults receiving care for colorectal cancer in an outpatient...