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Skip to Search Results- 33Graduate and Postdoctoral Studies (GPS), Faculty of
- 33Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 16Nursing, Faculty of
- 12Nursing, Faculty of/Chronicity
- 3Joel Martin Halpern Image Archive
- 3Joel Martin Halpern Image Archive/Northern North America Collection
- 33Thesis
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2012
Mendelsohn, M., Lischka, A.R., Overend, T., Forbes, D.
Early detection of dementia is essential to guide front-line health care practitioners in further clinical evaluations and treatments. There is a paucity of literature assessing the effectiveness of screening tools to predict the development of dementia, thus we conducted a systematic review to...
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Fall 2013
Purpose: evaluate 1) reliability and accuracy of cone-beam computed tomography (CBCT) for assessing adenoid size compared to nasoendoscopy (NE), 2) Influence of clinical experience on CBCT diagnosis. Methods: Four blinded evaluators reviewed randomized CBCT images. Adenoid size was graded on a...
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Spring 2016
There is ample evidence that autophagy is affected in Alzheimer’s disease (AD) but the causes, the nature of the dysfunction and the mechanisms of autophagy impairment are unclear. Autophagy depends on vesicular trafficking and membrane fusion, events that rely on several protein complexes and...
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Fall 2019
Alzheimer’s disease (AD) is characterized by the accumulation of amyloid beta (Aβ) peptide. It has been proposed that AD pathology is transmissible by a “prion-like” mechanism through extracellular vesicles (EVs) that contain Aβ. In this context, EVs describe both microvesicles and exosomes,...
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Fall 2014
While there has been much literature in the area of system monitoring and diagnosis, most of these techniques have a relatively small scope in terms of the faults and performance issues that they are built to detect. When implementing several monitors simultaneously on a single process, a single...
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Spring 2014
Clients with cybersex addiction (CSA) are a growing challenge for mental health practitioners. Therapists must be more skilled and adept at identifying when the core issue is cybersex addiction in spite of client denial and potentially confounding symptoms. The main purpose of this exploratory...
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Cellular level/distribution of γ-secretase subunit nicastrin and its modulator p23 in the brain
DownloadSpring 2010
The processing of amyloid precursor protein (APP) by β- and γ-secretases produces amyloid β (Aβ) peptide, the principal component of the neuritic plaques found in Alzheimer’s disease (AD) pathology. The enzyme γ-secretase is a multimeric protein consisting of presenilins-1/2 (PS1/PS2), nicastrin,...
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Challenges for Resource Allocation, Decision Making and Consideration of Social Values for Screening, Diagnosis and Treatment of Hepatitis C in Canadian Populations
DownloadFall 2018
Introduction: Health care system decision makers face challenges in allocating resources for screening, diagnosis and therapies for hepatitis C, caused by the highly infectious and blood borne hepatitis C virus (HCV) (WHO, 2014). Approximately 240,000 individuals are infected with HCV in Canada...