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Skip to Search Results- 12Next-generation sequencing
- 3MicroRNAs
- 2Alberta
- 2Alternative Splicing
- 2Amplicon
- 2Canada, Alberta, Fort McMurray
- 10Graduate and Postdoctoral Studies (GPS), Faculty of
- 10Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 2Oil Sands Research and Information Network (OSRIN)
- 2Oil Sands Research and Information Network (OSRIN)/OSRIN Technical Reports
- 1Agricultural, Food and Nutritional Science, Department of
- 1Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Application of Next Generation Sequencing and Bioinformatic Approaches to the Study of Influenza Virus Strains and MiRNA Profiling in Liver Diseases
DownloadSpring 2016
Analysis and interpretation of next generation sequencing data has posed a significant challenge to researchers, especially to those who are not equipped with expertise in bioinformatics. In this thesis, I investigated three different biomedical questions using NGS and bioinformatic approaches,...
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Characterization of Norovirus strains and a seroprevalence study to understand the fluctuation of outbreak activity in Alberta, Canada
DownloadFall 2016
Norovirus (NoV) is recognized as the leading agent causing gastroenteritis among individuals of all ages. Historical data of NoV outbreak surveillance in Alberta, Canada, from the period July 2000 to June 2008 demonstrated a biennial pattern of NoV outbreak activity, in which peaks of high...
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Combined Assembly of Metagenomic Libraries from The Faecal Samples of IBD and PSC Patients Allowed The Identification of African Swine Fever Virus-like Sequences
DownloadSpring 2015
Metagenomics is an emerging discipline to explore microbial diversity in clinical samples, independent of the limitations of cell cultures. This method is widely accepted as a modern technique to detect novel viruses in clinical and environmental samples and has the potential to contribute to the...
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Examining the Effects of Cytoplasmic Tail Splicing Event in Goldfish (Carassius auratus) Leukocyte Immune-type receptors
DownloadSpring 2024
The innate immune system is important in clearing infections and maintaining homeostasis. Across vertebrates, innate immunity is capable of executing potent effector responses through the actions of highly specialized cells. Effector responses, such as phagocytosis and cytokine secretion, are...
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Next Generation Sequencing of Protists as a Measure of Microbial Community in Oil Sands Tailings Ponds: Amplicon Versus Metagenomic Approaches
Download2014-11-21
Aquilar, M., Glücksman, E., Bass, D., Dacks, J.B.
The Alberta oil sands provide a major benefit to the province as an economic driver. At the same time, their responsible exploitation, particularly in mitigating the environmental impact of oil extraction stands as a significant challenge to be addressed. One of the most contentious aspects is...
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Next-Generation Sequencing of Protists as a Measure of Natural Soil Microbial Eukaryotic Community in the Oil Sands Region
Download2012-12-23
Quideau, S., Richardson, E., Dacks, J.B., MacIntyre, G., Adl, S., Walker, G.
Soil plays a central role in the functioning of all terrestrial ecosystems. Among the many ecosystem services to which soil contributes are: purification and storage of water, sequestration of organic matter, nutrient cycling for plant growth, and conservation of healthy faunal and microbial...
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Profiling and Identification of Post-Transcriptional Regulatory Molecules for Human Cancer Cachexia
DownloadSpring 2017
Cancer cachexia (CC) is a multifactorial syndrome characterized by severe depletion of skeletal muscle, with or without fat loss. A majority of cancer patients with incurable cancer are affected with cachexia and it remains an unmet medical need. Gene expression changes at the transcriptional...
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Profiling and Identification of Small Non-coding RNAs as Prognostic Markers for Breast Cancer
DownloadFall 2016
Breast cancer (BC) continues to be one of the leading causes of cancer related death among women. Despite continuous progress in screening, diagnosis and treatment of BC, a subset of patients experience recurrence and/or death. Optimal management of BC has remained a challenge due to these...
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2017-05-16
Megha, Swati, Kav, Nat N. V., Basu, Urmila
Low temperature is one of the most common environmental stresses that seriously affect the growth and development of plants. However, plants have the plasticity in their defence mechanisms enabling them to tolerate and, sometimes, even survive adverse environmental conditions. MicroRNAs (miRNAs)...