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Skip to Search Results- 8University of Alberta, Department of Biological Sciences
- 7Wang, J.
- 5Wishart, D.S.
- 4Stothard, Paul
- 4Wong, Gane K.
- 4Yu, Jun
- 59Graduate and Postdoctoral Studies (GPS), Faculty of
- 59Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 40Biological Sciences, Department of
- 32Biological Sciences, Department of/Journal Articles (Biological Sciences)
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- 8Agricultural, Food and Nutritional Science, Department of
- 59Thesis
- 51Article (Published)
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Characterisation of the Non-Canonical Translation Initiation Factor eIF4E-3 as a Merlin Interacting Protein in Drosophila melanogaster
DownloadSpring 2016
Merlin is a tumour suppressor protein, the loss of which is linked to the inherited nervous system tumour syndrome Neurofibromatosis type 2 as well as sporadic tumour development. It is related to the ERM (ezrin-radixin-moesin) protein family, which is involved in linking the cytoskeleton to...
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Fall 2017
Merlin and the ezrin-radixin-moesin (ERM) proteins are key organizers of the cell cortex through linking membrane-associated proteins to the underlying actin cytoskeleton. Merlin and the ERM proteins have been implicated in the maintenance of cell integrity, adhesion, and motility during tissue...
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Characterization of the crosstalk between immunity and metabolism in Drosophila melanogaster model
DownloadFall 2021
Immune and metabolic pathways collectively contribute to the containment of microbial invaders, and persistent activation of immune responses contribute to the development of severe metabolic disorders. To determine how interaction between innate immune system and metabolic responses affected...
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2000-08-01
Wang, Jian, Burnett, John R., Near, Susan, Young, T. Kue, Zinman, Bernard, Hanley, Anthony J. G., Connelly, Philip W., Harris, Stewart B., Hegele, Robert A.
"Mutations in ABCA1, a member of the ATP-binding cassette family, have been shown to underlie Tangier disease (TD) and familial hypoalphalipoproteinemia (FHA), which are genetic disorders that are characterized by depressed concentrations of plasma high density lipoprotein (HDL) cholesterol. An...
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Spring 2023
The increased availability and use of assisted reproductive technologies, legislative changes that recognize equal marriage, and the expansion of legal parentage beyond “the rule of two” are inviting Canadians to reimagine fundamental questions about kinship, parentage, and legal recognition. My...
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1992-01-01
Caceres, J.F., McKenzie, D.I., Thimappaya, R., Lund, E., Dahlberg, J.E.
The expression of mouse embryonic U1 snRNA (mU1b) genes is subject to stage- and tissue-specific control, being restricted to early embryos and adult tissues that contain a high proportion of stem cells capable of further differentiation. To determine the mechanism of this control we have sought...