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Skip to Search Results- 7Strain, Laurel A.
- 7Wanless, Deanna
- 4Forbes, D.
- 3Ghali, W.A.
- 3Maxwell, Colleen J.
- 2ACCES Research Group
- 36Graduate and Postdoctoral Studies (GPS), Faculty of
- 36Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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- 3Dixon, Roger (Psychology)
- 2Cummine, Jacqueline (Communication Sciences and Disorders)
- 1Ben Zvi, Ehud (History & Classics)
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- 1Darren DeLorey, PhD Faculty of Physical Education and Recreation; Rehabilitation Medicine
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Fall 2020
BACKGROUND: Parkinson’s disease (PD) is a progressive, neurodegenerative disorder characterized by resting tremors, instability, slowness of movement and rigidity, generally accompanied by non-motor symptoms such as mood disturbance, fatigue, constipation, incontinence and sleep disorders. Any...
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Does methylation of the brain promoter region of Cyp19 impact the development of sex-typical psychological traits?
DownloadFall 2017
While humans demonstrate sexually differentiated psychological and behavioural traits, such as aggression, there is a vast amount of within-sex variation for these traits. Further, the effect size of these sex differences is relatively small and there is a large amount of overlap between males...
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Effect of dietary nitrate on sympathetic vasoconstriction in resting and contracting skeletal muscle
DownloadFall 2015
Dietary nitrate (NO3-) may increase nitric oxide (NO) bioavailability and alter the control of blood flow at rest and during exercise. This thesis investigated the effect of dietary NO3- supplementation on sympathetic mediated control of skeletal muscle blood flow in resting and contracting...
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Fall 2021
Chronological aging is one of the greatest risk factors of tauopathies, yet our understanding about the underlying molecular mechanism is limited. Studying physiological aging often requires an extended timeline and thus presents a significant hurdle for modeling late-onset disorders. In this...
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Effects of Tripeptide IRW (Ile-Arg-Trp) on metabolism, mitochondrial biogenesis, and lifespan extension
DownloadSpring 2022
Bioactive tripeptide IRW (Ile-Arg-Trp) was initially identified as an ACE (angiotensin-converting enzyme) inhibitory peptide from egg protein ovotransferrin. The pharmacological spectrum of IRW extends towards metabolic boosting and anti-diabetic properties as well. The overall objectives of this...
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Exploring barriers and facilitators to the implementation of healthy aging policy in suburban planning and transportation departments
DownloadSpring 2011
Purpose: The purpose of this research was examine potential barriers and facilitators to the implementation of healthy public policy related to aging, specifically in municipal planning and transportation departments, in the suburban context. Research Questions: What are the factors which...
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Family members providing home-based palliative care to older adults: The enactment of multiple roles
Download2008
Clemmer, S., Ward-Griffin, C., Forbes, D.
Canadians are experiencing increased life expectancy and chronic illness requiring end-of-life care. There is limited research on the multiple roles for family members providing home-based palliative care. Based on a larger ethnographic study of client-family-provider relationships in home-based...
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Insulin signaling, mitochondrial DNA copy number regulation and aging in Caenorhabditis elegans
DownloadFall 2010
Mitochondrial dysfunction is considered as a key mechanism of aging but little is known about the impact of mitochondrial biogenesis. Mitochondrial DNA (mtDNA) copy number control is an important aspect of mitochondrial biogenesis and is highly regulated in eukaryotic organisms. By studying mtDNA...
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Integrating Characteristics of Executive Functions in Non-Demented Aging: Structure, Trajectories, Classification, and Biomarker Predictors
DownloadSpring 2019
In aging, executive function (EF) performance (level) and change (trajectory) are linked to multiple interacting risk factors. Structurally, EFs have previously been represented as either a unitary (e.g., unidimensional) or diverse (e.g., multidimensional) set of abilities that change across the...