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Understanding implementation processes of clinical pathways and clinical practice guidelines in pediatric contexts: A study protocol
Download2011
Nettel-Aguirre, A., Klassen, T.P., Grimshaw, J., Johnson, D., Scott, S.
Background: Canada is among the most prosperous nations in the world, yet the health and wellness outcomes of Canadian children are surprisingly poor. There is some evidence to suggest that these poor health outcomes are partly due to clinical practice variation, which can stem from failure to...
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Virus Induced Asthma Exacerbations: Immunologic Mechanisms and Metabolomic Biomarkers
2014-03-30
Asthma is a complex multifaceted chronic inflammatory disease that is characterized clinically by reversible airflow obstruction, shortness of breath, coughing, and wheezing. Asthma is the most common chronic disease in children, and is differentiated into many phenotypes with multiple triggers....
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Fall 2014
Epidemiological studies correlate vitamin D deficiency with asthma severity. Calcitriol modulates receptor and cytokine expression from various leukocytes in an anti-inflammatory manner. Despite eosinophil activity during mucosal inflammation, knowledge on the direct effect of calcitriol on this...