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Skip to Search Results- 1Anderson, Sarah J
- 1Atchison, Bobbi-Jo L
- 1Badejo, Ifueko
- 1Barlott, Timothy
- 1Beggs, Megan R
- 1Biswas, Afrin Anowar
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Fall 2013
It is often assumed during product design that the product will be used by individuals who have two working eyes, ears, legs, feet, hands in addition to the ability to mentally process information in a very coherent way. Such assumptions during the design process negate the experiences of people...
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Characterization of Human Pancreatic Beta-cell Progenitors as a Means to Alleviate the Shortage of Donor Tissue for Islet Transplantation
DownloadFall 2012
The current shortage of islet tissue from cadaveric human donors is not sustainable and will preclude islet transplantation from becoming a widespread therapeutic treatment for those with type 1 diabetes. A potential alternative source of tissue may be through isolating, expanding, and...
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Characterizing the role of the endocannabinoid system’s catabolic enzymes FAAH and MAGL in the development of functional sensorimotor activities in zebrafish
DownloadFall 2022
The endocannabinoid system (eCS) plays a critical role in a variety of homeostatic and developmental processes. Generally, the eCS relies on the naturally produced compounds known as endocannabinoids (eCBs), which are lipophilic signaling molecules that interact with cannabinoid receptors to...
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Conserving cougars in a rural landscape: habitat requirements and local tolerance in west-central Alberta
DownloadSpring 2011
Maintaining large carnivores in human-dominated landscapes poses a significant conservation challenge. Extirpation is common because of habitat loss or direct persecution. I studied cougar habitat selection and human perception of cougars in west-central Alberta to better understand...
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Delineation of molecular mechanisms of intestinal calcium absorption during postnatal development
DownloadFall 2021
Infants and children must maintain a positive calcium balance for appropriate growth. Evidence suggests that adaptations in intestinal absorption of calcium are the major determinant of this net balance. However, the molecular details of the pathways mediating this increased absorption at a young...
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Development and Evolution of Complex Reproductive Traits in the Brassicaceae and Cleomaceae
DownloadSpring 2023
Flowering plants exhibit a bewildering diversity of forms, which raises fundamental questions on how that diversity arises. A cornerstone of evolutionary developmental biology is the expansion of comparative landscapes and establishment of focal clades that enable investigation of complex and...
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Fall 2023
Motoneuron properties and their firing patterns undergo significant changes throughout development and in response to neuromodulators like serotonin. In this thesis we examined intrinsic motoneuron properties in 50 typically developing participants ranging in age from 7 to 53 years. The primary...
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Development of the Voltage-Gated Sodium and Potassium Currents Underlying Excitability in Zebrafish Skeletal Muscle
DownloadFall 2009
Excitable cells display dynamically regulated changes in the properties of ion currents during development. These changes are crucial for the proper maturation of cellular excitability, and therefore have the potential to affect more sophisticated functions, including neural circuits, movements,...
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Development, Anatomy, and Phylogenetic Relationships of Jawless Vertebrates and Tests of Hypotheses about Early Vertebrate Evolution
DownloadSpring 2018
The origin and early evolution of vertebrates remain one of the central questions of comparative biology. This clade, which features a breathtaking diversity of complex forms, has generated profound, unresolved questions, including: How are major lineages of vertebrates related to one another?...