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Skip to Search Results- 2Al-Hallak, MHD Kamal
- 1Acton, Leah T
- 1Airo, Adriana M
- 1Anwar-Mohamed, Anwar
- 1Azarmi, Shirzad
- 1Badr, Dina EFA
- 22Graduate and Postdoctoral Studies (GPS), Faculty of
- 22Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 1Pharmacy and Pharmaceutical Sciences, Faculty of
- 1Pharmacy and Pharmaceutical Sciences, Faculty of/Journal Articles (Pharmacy and Pharmaceutical Sciences)
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/Other Publications (Biological Sciences)
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Fall 2020
RNA helicases function in all aspects of RNA metabolism, regulating a diverse range of cellular processes by rearranging RNA structures and mediating RNA-protein interactions. Prokaryotic RNA helicases have been shown to have roles in RNA degradation, ribosome biogenesis and translation, with...
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Fall 2013
West Nile virus (WNV) is a neurotropic, blood-borne flavivirus that can cause serious neurological disease in humans and animals. While significant progress has been made in identifying virus-encoded pathogenic determinants, very little is known regarding how these viral proteins interact with...
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Inhalable nanoparticles in lung cancer treatment; efficacy, safety, distribution and nanoparticle-macrophage interactions
DownloadFall 2012
In 2002, lung cancer was responsible for 17.6% of the total worldwide deaths from cancer. Beyond the three traditional forms of cancer treatment, surgery, radiation therapy, and chemotherapy, targeted drug delivery therapy has shown to be a potential treatment option. The design of a successful...
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Fall 2017
The two types of rejection identified in the Banff histopathologic diagnosis are T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR). TCMR is most common early post-transplant while ABMR is the main cause of late graft loss. Kidney transplant TCMR is diagnosed histologically...
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Investigating Mechanisms Responsible for the Pro-Regenerative Effects of Conditioning Electrical Stimulation
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Though capable of regeneration, repair surgeries following peripheral nerve injury are often incomplete or entirely unsuccessful. The slow rate of regeneration (1-3mm/day) of a proximal injury requires up to two years to reach the distal target, whereas significant muscle atrophy occurs after...
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Spring 2020
The human neuraminidases (NEU1, NEU2, NEU3, and NEU4) are a family of enzymes implicated in pathologies including cancer and diabetes. Our group has developed selective inhibitors for these enzymes that have been employed as tools to understand their biological roles. Several reports have linked...
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2012-06-21
Whitford, Denise S., Owttrim, George W.
Expression of the stress-regulated RNA helicase of Synechocystis sp. PCC 6803, CrhR, is altered by three known stresses, temperature, light and salt concentration. Here we show that altering the source of fixed nitrogen, either urea, ammonia, nitrate or lack of fixed nitrogen, also results in...