Search
Skip to Search Results- 14Young, T. Kue
- 5Willows, Noreen D.
- 4Hegele, Robert A.
- 4Prado, Carla M.
- 3Field, Catherine J.
- 3Proctor, Spencer D.
- 52Graduate and Postdoctoral Studies (GPS), Faculty of
- 52Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 17Agricultural, Food and Nutritional Science, Department of
- 17Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 16School of Public Health
- 16School of Public Health/Journal Articles (Public Health)
-
Prevalence of Obesity and Its Metabolic Correlates Among the Circumpolar Inuit in 3 Countries
Download2007
Young, T. Kue, Bjerregaard, Peter, Dewailly, Eric, Risica, Patricia M., Jørgensen, Marit E., Ebbesson, Sven E. O.
"Objectives: We investigated the prevalence of obesity and the metabolic correlates of different levels of body mass index (BMI) and waist circumference among the Inuit in 3 countries. Methods: Data from 4 surveys of Inuit in Canada, Greenland, and Alaska conducted during 1990–2001 were pooled,...
-
Profiling the Bacterial and Fungal Gut Microbiome of Children with and without Prader-Willi Syndrome (PWS)
DownloadFall 2020
Obesity is a complex multifactorial disease that has a large array of direct (e.g. altered metabolic and inflammatory profile) and indirect (e.g. mental health concerns etc.) consequences on health and is associated with increased morbidity and mortality. Prader-Willi Syndrome (PWS) is the most...
-
Promoter Polymorphism in PCK1 (Phosphoenolpyruvate Carboxykinase Gene) Associated with Type 2 Diabetes Mellitus
Download2004-02-01
Cao, Henian, van der Veer, Eric, Ban, Matthew R., Hanley, Anthony J.G., Zinman, Bernard, Harris, S. B., Young, T. Kue, Pickering, J. Geoffrey, Hegele, Robert A.
"We sequenced the promoter and coding regions of PCK1 encoding cytosolic phosphoenolpyruvate carboxykinase from genomic DNA of subjects with type 2 diabetes mellitus (DM). We found nine single nucleotide polymorphisms (SNPs) that were present with varying allele frequencies and pairwise linkage...
-
2009
Lix, Lisa M., Bruce, Sharon, Sarkar, Joykrishna, Young, T. Kue
"Background: In Canada, the prevalence of behavioural risk factors and chronic conditions differs for Aboriginal and non-Aboriginal populations, but little research has examined changes over time. This study compares several major risk factors and chronic conditions in Aboriginal and...
-
Fall 2014
Cardiac Fatty acids β-oxidation (FAO) markedly increases during maturation and become the major source of energy for the adult heart. However, excessive rates of FAO can compromise cardiac function in obesity, diabetes, and heart failure. Lysine acetylation has recently been identified as a...
-
2011-07-01
Ng, Carmina, Corey, Paul N., Young, T. Kue
"Objectives: Large disparities exist between Aboriginal and non-Aboriginal Canadians in both obesity and socio-economic status (SES). The purpose of this paper was to assess associations between obesity and three indicators of SES–employment, education and income–in conjunction with demographic...
-
2012
Birch, Daniel W., Gill, Richdeep S., Karmali, Shahzeer, Whitlock, Kevin
Obesity has become a major issue for healthcare providers as its prevalence continues to increase throughout the world. The literature suggests that increased body mass index (BMI) is associated with the development of certain cancers such as colorectal cancer (CRC). Consequently, CRC surgeons...
-
The current recommended vitamin D intake guideline for diet and supplements during pregnancy is not adequate to achieve vitamin D sufficiency for most pregnant women
Download2016
Maggiore, Jack A., Eliasziw, Misha, Rabi, Doreen, O'Beirne, Maeve, Field, Catherine J., Hanley, David A., Dewey, Deborah, Aghajafari, Fariba, Weinberg, Amy, Kaplan, Bonnie J., Ross, Sue
Background The aims of this study were to determine if pregnant women consumed the recommended vitamin D through diet alone or through diet and supplements, and if they achieved the current reference range vitamin D status when their reported dietary intake met the current recommendations....
-
The Effects of Elements of Cardiometabolic Syndrome on Metformin Disposition: Obesity and Hyperlipidemia
DownloadFall 2015
The influences of obesity, Roux-en-Y gastric bypass bariatric (RYGB) surgery and hyperlipidemia on metformin pharmacokinetics (PK) were investigated. A sensitive and novel HPLC-UV reverse phase assay method was developed and utilized. Detection and mass characterization for metformin metabolites...