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Skip to Search Results- 81Graduate and Postdoctoral Studies (GPS), Faculty of
- 81Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 10Medicine and Dentistry, Faculty of
- 9Medicine and Dentistry, Faculty of/Alberta Research Centre for Health Evidence (ARCHE)
- 7Agricultural, Food and Nutritional Science, Department of
- 7Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Fall 2016
Background. Tools and resources (TRs) can help to prevent obesity in children, particularly in settings that are accessible to families and well-aligned with chronic disease prevention, such as primary care. To date, little is known about the TRs that primary care providers (PCPs) currently use...
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Towards superior cancer drugs by modeling approaches: Modification and prediction of the mode of action
DownloadFall 2021
Cancer is a leading cause of death that imposes significant economic and social suffering on a global scale. Based on the projected growth and ageing of populations, the global burden of cancer is set to increase. Despite the vast investment in cancer research, the rate of translation of research...
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Treatment in the pediatric emergency department is evidence based: a retrospective analysis.
Download2006
Wiebe, N., Waters, K. L., Cramer, K., Klassen, T. P., Hartling, L.
Background Our goal was to quantify the evidence that is available to the physicians of a pediatric emergency department (PED) in making treatment decisions. Further, we wished to ascertain what percentage of evidence for treatment provided in the PED comes from pediatric studies. Methods We...
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Fall 2012
There is limited information on families’ decisions regarding their (dis)continuation of weight management care. This thesis includes two complementary studies that examined this issue. First, an integrative review was performed to characterize predictors of and reasons for attrition in pediatric...
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Unveiling the pathway for the nuclear translocation of the large mitochondrial enzyme Pyruvate Dehydrogenase Complex (PDC)
DownloadSpring 2021
Pyruvate dehydrogenase complex (PDC) is a mitochondrial enzyme that links glycolysis to oxidative phosphorylation by decarboxylating glucose-derived pyruvate to produce acetyl-CoA that is used in the Krebs cycle. PDC was initially thought to reside only in the mitochondrial matrix but we recently...
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Utilization of national clinical practice guidelines: A survey of Canadian pediatric physicians
Download2015
Robinson Joan, Nicholson Katharine, Vandermeer Ben, Kumar Manoj, Nasir Fareeha
Background: It is not clear how physicians currently use clinical practice guidelines (CPGs). Objectives: The objective was to describe how Canadian pediatric residents and pediatricians use CPGs and to identify barriers to CPG use. Methods: Pediatric emergency physicians and general...
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Spring 2013
Objective: This study we explore the validity of using the uHearTM application on an Apple Incorporated’s, iOS product to test hearing thresholds in a pediatric population. Methods: 52 participants, ages 5 to12 had their hearing tested in 3 ways. A portable screening audiometer was used as the...
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Versatile Polymer-Based Nanomedicines for Drug/Gene Delivery and Cell-based Therapy Applications
DownloadSpring 2021
Advances in polymer science and nanotechnology have allowed the development of biomaterials for cell-based applications, such as the delivery of a variety of drugs and genes, as well as supporting technologies, such as stem cell therapies, tissue engineering and cryopreservation. The progress in...
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Vitamin D Status and Markers of Cardiometabolic and Liver Disease Risk in Childhood Obesity
DownloadSpring 2017
Vitamin D insufficiency is highly prevalent in children (up to 40%), particularly in northern climates such as Alberta, due to reduced sunlight exposure and low intake. Although suboptimal vitamin D status and metabolic dysregulation are commonly observed in obesity, little is known about the...
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Spring 2017
Quantitative Magnetic Resonance Imaging (qMRI) is occupying an increasingly prominent role in the study of the brain, by virtue of its sensitivity to physiological and anatomical changes. However, because qMRI techniques tend to suffer from long scan durations and/or post-processing times, as...