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Skip to Search Results- 2Kinnaird, Adam
- 1Abdulsalam Alharbi
- 1Aktary, Zackie M
- 1Al Onazi, Mona Moraybed
- 1Alolayan, Waad Riyad
- 1Alshamsan, Aws
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Fall 2010
In many tumors, persistently-active signal transducer and activator of transcription 3 (STAT3) imparts several oncogenic features such as survival, proliferation, angiogenesis, and immune escape. Therefore, STAT3 targeting in cancer and cancer-exposed dendritic cells (DCs) is important for cancer...
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Fall 2017
For cancer research, a powerful imaging modality for both preclinical (where the focus is on imaging small animals) and clinical (where the focus is on imaging human subjects) applications should be inexpensive, portable, noninvasive, safe, and capable of measuring a myriad of information....
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Drug Resistance in Breast Cancer: Characterization of Rationally Designed Paclitaxel Analogs in Model Systems
DownloadFall 2013
Breast cancer is a leading cause of cancer related deaths among women in the developed world. Treatment options for breast cancer include taxanes, which mediate cytotoxic effects by inducing microtubule polymerization which impedes cell division. Taxane resistant breast cancer is a mounting...
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Evaluation of Hypoxia Induced Regulation of Nucleoside and Amino Acid Membrane Transporters in Breast Cancer
DownloadSpring 2020
Positron Emission Tomography (PET) utilizes radioactively tagged molecules to identify cancerous tissue. In most cases, membrane transporters control entry of these molecules into human cancer cells. Hypoxia-inducible factor (HIF)-1 is the master homeostatic regulator during hypoxia in human...
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Spring 2019
Energy expenditure forms the basis of all dietary recommendations. In patients with cancer, resting energy expenditure (REE) can be impacted by tumor burden, high systemic inflammation, and/or altered body composition. Total energy expenditure (TEE) and physical activity levels (PAL) have been...
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Fall 2020
Background: A standard treatment option for locally advanced rectal cancer includes 5-6 weeks of neoadjuvant chemoradiation (NACRT) followed by surgery about 6-8 weeks later. NACRT improves outcomes for rectal cancer patients but also causes acute toxicities which may impede quality of life...
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Food intake behaviour in advanced cancer – implications of taste and smell alterations, orosensory reward, and cannabinoid therapy
DownloadFall 2009
Food intake is regulated by both appetite and orosensory reward systems. Appetite systems stimulate or reduce hunger, while orosensory reward motivates consumption of high fat sweet foods, resulting in food enjoyment. The majority of advanced cancer patients suffer from malnutrition and wasting,...
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Giving Voice to the Unheard: Perceptions, Practices & Beliefs About Breast Cancer and Screening Among Ethnic Minority Women From the MENA (Middle East & North Africa) Region in Edmonton, Alberta.
DownloadFall 2019
Breast cancer is one of the major causes of death among women in Canada and globally. In Canada, screening has been found to be successful in decreasing morbidity and mortality (Canadian Cancer Society, 2015). Use of breast cancer screening services by immigrant women however is limited...
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Identifying Major Depressive Symptoms and Major Depressive Episodes in Adolescents with Cancer
DownloadFall 2015
Cancer is the leading cause of death from disease among adolescents in Canada. Although cancer is a well-researched disease process in the medical and nursing literature, adolescence is relatively understudied, with minimal evidence on strategies to promote healthy emotional adjustment...
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Imag(in)ing the cancerous body: representations of cancer in medical discourse and contemporary visual art
DownloadFall 2010
This thesis examines representations of cancer in contemporary art, with a particular focus on unruly, un-idealized bodies at risk. In bringing together the discourses of art history and medicine, its aim is to engage conventions of visualizing cancer, and more importantly, to highlight the ways...