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2005

Wishart, David S., Shrivastava, Savita, Ellison, Michael, Guo, Anchi, Cruz, Joseph, van Domselaar, Gary, O'Neill, Brian, Stothard, Paul

BacMap is an interactive visual database containing fully labeled, zoomable and searchable chromosome maps from more than 170 bacterial (archaebacterial and eubacterial) species. It uses a recently developed visualization tool (CGView) to generate high-resolution circular genome maps from...

2012

Wishart, David S., Cruz, Joseph, Tang, Peter, Stothard, Paul, Zhou, Jianjun, Berjanskii, Mark, Liang, Yongjie, Lu, Paul, Zhou, You, Lin, Gouhui, MacDonell, Cam

Originally released in 2005, BacMap is an electronic, interactive atlas of fully sequenced bacterial genomes. It contains fully labeled, zoomable and searchable chromosome maps for essentially all sequenced prokaryotic (archaebacterial and eubacterial) species. Each map can be zoomed to the level...

2005

Dong, Xaoli, Wishart, David S., Stothard, Paul, Greiner, Russ, Guo, AnChi, van Domselaar, Gary H., Szafron, Duane, Shrivastava, Savita, Cruz, Joseph A., Lu, Paul

BASys (Bacterial Annotation System) is a web server that supports automated, in-depth annotation of bacterial genomic (chromosomal and plasmid) sequences. It accepts raw DNA sequence data and an optional list of gene identification information and provides extensive textual annotation and...

2012

Stothard, Paul, Arantes, Adriano S., Grant, Jason R.

Background Continued sequencing efforts coupled with advances in sequencing technology will lead to the completion of a vast number of small genomes. Whole-genome comparisons represent an important part of the analysis of any new genome sequence, as they can provide a better understanding of the...

2006

Chang, Zhan, Hassanali, Murtaza, Wishart, David S., Stothard, Paul, Woolsey, Jennifer, Guo, AnChi, Shrivistava, Savita, Knox, Craig

DrugBank is a unique bioinformatics/cheminformatics resource that combines detailed drug (i.e. chemical) data with comprehensive drug target (i.e. protein) information. The database contains >4100 drug entries including >800 FDA approved small molecule and biotech drugs as well as >3200...

2008

Cheng, Dean, Stothard, Paul, Damaraju, Sambasivarao, Wishart, David S., Knox, Craig, Young, Nelson

A particular challenge in biomedical text mining is to find ways of handling ‘comprehensive’ or ‘associative’ queries such as ‘Find all genes associated with breast cancer’. Given that many queries in genomics, proteomics or metabolomics involve these kind of comprehensive searches we believe...

2011

Liao, Xiaoping, Choi, Jung-Woo, Stothard, Paul, Basu, Urmila, Sumner-Thomson, Jennifer M., Meng, Yan, Moore, Stephen S.

Background One of the goals of livestock genomics research is to identify the genetic differences responsible for variation in phenotypic traits, particularly those of economic importance. Characterizing the genetic variation in livestock species is an important step towards linking genes or...

2015

Stothard, Paul, Wang, Yining, Lin, Guohui, Wylie, Tim

Background Despite ongoing reductions in the cost of sequencing technologies, whole genome SNP genotype imputation is often used as an alternative for obtaining abundant SNP genotypes for genome wide association studies. Several existing genotype imputation methods can be efficient for this...