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Structure-function relationships of antifungal monohydroxy unsaturated fatty acids (HUFA) of plant and bacterial origin
Download2020-08-01
Liang, Nuanyi, Dacko, Andrea, Tan, Alexander K., Xiang, Sheng, Curtis, Jonathan M., Gänzle, Michael G.
This study investigated the relationships between the structures of hydroxy unsaturated fatty acids (HUFA) and their antifungal activities. Structurally diverse HUFA, including four monohydroxy-18:1 isomers, two monohydroxy 18:2 isomers and two monohydroxy 18:2 isomers were extracted from seeds...
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Structure-function relationships of bacterial and enzymatically produced reuterans and dextran in sourdough bread baking application
Download2015-12-19
Chen, Xiao Yan, Levy, Clemens, Gänzle, Michael G.
Exopolysaccharides from lactic acid bacteria may improve texture and shelf life of bread. The effect of exopolysaccharides on bread quality, however, depends on properties of the EPS and the EPS producing strain. This study investigated structure-function relationships of EPS in baking...
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The effect of growth temperature, process temperature, and sodium chloride on the high pressure inactivation of Listeria monocytogenes on ham
Download2016-01-01
Teixeira, Januana S., Maier, Maximilian B., Miller, Petr, Gänzle, Michael G., McMullen, Lynn M.
This study investigated the effect of growth temperature (8–32 °C), process temperature (−17 to 32 °C), and sodium chloride concentration (0–3 %) on the lethality of pressure to Listeria monocytogenes. Pressure treatments were performed using a 5-strain cocktail of L. monocytogenes. Cultures...
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The locus of heat resistance (LHR) mediates heat resistance in Salmonella enterica, Escherichia coli and Enterobacter cloacae
Download2017-06-01
Mercer, Ryan G., Walker, Brian D., Yang, Xianqin, McMullen, Lynn M., Gänzle, Michael G.
Enterobacteriaceae comprise food spoilage organisms as well as food-borne pathogens including Escherichia coli. Heat resistance in E. coli was attributed to a genomic island called the locus of heat resistance (LHR). This genomic island is also present in several other genera of...
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The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in rats
Download2014
Baracos, Vickie, Dieleman, Levinus, Farhangfar, Arazm, Lin, Xiaoxi B., Gänzle, Michael G., Sawyer, Michael B., Valcheva, Rosica, Schieber, Andreas
CPT-11 is a drug used as chemotherapy for colorectal cancer. CPT-11 causes toxic side-effects in patients. CPT-11 toxicity has been attributed to the activity of intestinal microbiota, however, intestinal microbiota may also have protective effects in CP!-11 chemotherapy. This study aimed to...