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Author / Creator / Contributor
- 1Aguzzi, Adriano
- 1Baral, Pravas K.
- 1James, Michael N. G.
- 1Kav, Nat N. V.
- 1Polymenidou, Magdalini
- 1Swayampakula, Mridula
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Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody
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James, Michael N. G., Swayampakula, Mridula , Polymenidou, Magdalini , Kav, Nat N. V., Aguzzi, Adriano, Wieland, Barbara, Baral, Pravas K.
Prion diseases are neurodegenerative diseases that are characterized by the conversion of the cellular prion protein PrPc to the pathogenic isoform PrPsc. Several antibodies are known to interact with the cellular prion protein and to inhibit this transition. An antibody Fab fragment, Fab POM1,...
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