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Skip to Search Results- 8Sawyer, Michael B.
- 6Koleva, Petya
- 5Gänzle, Michael G.
- 5Prado, Carla M.
- 5Xue, Hongyu
- 4Baracos, Vickie E.
- 14Agricultural, Food and Nutritional Science, Department of
- 14Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 4WISEST Summer Research Program
- 4WISEST Summer Research Program/WISEST Research Posters
- 1Graduate and Postdoctoral Studies (GPS), Faculty of
- 1Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
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A Nutritional Perspective of Ketogenic Diet in Cancer: A Narrative Review
2018-04-01
Oliveira, Camila L. P., Mattingly, Stephanie, Schirrmacher, Ralf, Sawyer, Michael B., Fine, Eugene J., Prado, Carla M.
The predominant use of glucose anaerobically by cancer cells (Warburg effect) may be the most important characteristic the majority of these cells have in common and, therefore, a potential metabolic pathway to be targeted during cancer treatment. Because this effect relates to fuel oxidation,...
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Chemically defined diet alters the protective properties of fructo-oligosaccharides and isomalto-oligosaccharides in HLA-B27 transgenic rats
Download2014
Koleva, Petya, Ketabi, Ali, Dieleman, Levinus A., Gänzle, Michael G., Valcheva, Rosica
Non-digestible oligosaccharides (NDO) were shown to reduce inflammation in experimental colitis, but it remains unclear whether microbiota changes mediate their colitis-modulating effects. This study assessed intestinal microbiota and intestinal inflammation after feeding chemically defined...
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2023-03-01
Ford, Katherine L., Trottier, Claire F., Wismer, Wendy V., Sawyer, Michael B., Siervo, Mario, Deutz, Nicolaas E.P., Prado, Carla M., Vallianatos, Helen
Background Dietary changes often accompany management of a cancer diagnosis, but how and why patients with colorectal cancer (CRC) make dietary decisions requires further investigation. Objective To learn about patients’ food-related beliefs and understand whether and why dietary changes were...
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Environmental particulate matter induces murine intestinal inflammatory responses and alters the gut microbiome
Download2013-01-01
Thiesen, Aducio, Rioux, Kevin P., Tso, Robert, Kish, Lisa, Barkema, Herman W., Madsen, Karen L., Vincent, Renaud, Wine, Eytan, Kaplan, Gilaad G., Hotte, Naomi, Gänzle, Michael G.
Background Particulate matter (PM) is a key pollutant in ambient air that has been associated with negative health conditions in urban environments. The aim of this study was to examine the effects of orally administered PM on the gut microbiome and immune function under normal and inflammatory...
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Gene-expression profiling of calves 6 and 9 months after inoculation with Mycobacterium avium subspecies paratuberculosis
Download2014
David, Joel, De Buck, Jeroen, Barkema, Herman W., Guan, Leluo
Early detection of Johne's disease (JD) caused by Mycobacterium avium subspecies paratuberculosis (MAP) is essential to reduce transmission; consequently, new diagnostic techniques and approaches to detect MAP or markers of early MAP infection are being explored. The objective was to identify...
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Inulin and fructo-oligosaccharides have divergent effects on colitis and commensal microbiota in HLA-B27 transgenic rats
Download2012-01-01
Koleva, Petya, Dieleman, Levinus, Sun, Xu, Gänzle, Michael G., Valcheva, Rosica
Modulation of intestinal microbiota by non-digestible carbohydrates may reduce inflammation in inflammatory bowel disease (IBD). The aim of the present study was to assess the effects of inulin and fructo-oligosaccharides (FOS) on intestinal microbiota and colitis in HLA-B27 transgenic rats, a...
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2012
Ketabi, Ali, Baracos, Vickie E., Field, Catherine J., Lin, Xiaoxi, Xue, Hongyu, Bibova, Ilona, Gänzle, Michael G., Dieleman, Levinus A., Sawyer, Michael B.
Intestinal microbiota mediate toxicity of irinotecan (CPT-11) cancer therapies and cause systemic infection after CPT-11-induced loss of barrier function. The intestinal microbiota and their functions are thus potential targets for treatment to mitigate CPT-11 toxicity. However, microbiota...
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2011-01-01
Xue, Hongyu, Field, Catherine J.
New role of glutamate as an immunoregulator via glutamate receptors and transporters.