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Skip to Search Results- 1Aguzzi, Adriano
- 1Baral, Pravas K.
- 1James, Michael N. G.
- 1Kav, Nat N. V.
- 1Polymenidou, Magdalini
- 1Rahman, Muhammad H.
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Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1
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Kav, Nat N. V., Polymenidou, Magdalini , Rahman, Muhammad H., Aguzzi, Adriano, Swayampakula, Mridula , James, Michael N. G., Baral, Pravas K., Wieland, Barbara
Prion diseases are neurodegenerative diseases characterized by the conversion of the cellular prion protein PrPc into a pathogenic isoform PrPsc. Passive immunization with antiprion monoclonal antibodies can arrest the progression of prion diseases. Here, the crystal structure of the Fab fragment...