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Regulation of Anti-tumor Immunity in Colorectal Cancer by Interaction of Exosome Immune Complexes with Fc gamma Receptors
DownloadSpring 2019
Targeted therapy is difficult for colorectal cancer (CRC) due to lack of conserved tumor associated antigens (TAA). Immunotherapies for CRC directed at TAA that can overcome intestinal tolerance need to be developed to improve survival of CRC patients. Exosomes are extracellular vesicles secreted...
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2022-09-26
Well-defined nano- and atomic-sized heterogeneous catalysts with extremely high catalytic activities and unique selectivities show promise in addressing the critical energy- and environment-related challenges of this century. The exceptional properties of these catalysts, such as their electronic...
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Prevalence, Characteristics, and Unmet Needs of Unbefriended Residents in Alberta Long-Term Care Homes
DownloadFall 2019
Background: Older adults who lack decision-making capacity and a willing or able surrogate to act as their representative are defined as unbefriended. These unbefriended older adults often require a public guardian and reside in long-term care (LTC) homes. Unbefriended LTC residents are at risk...
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Precious metal, Lu-Hf, and Re-Os geochemistry of the metasomatized lithospheric mantle: implications for subcrustal precious metal mobilization and MARID petrogenesis
DownloadFall 2022
The connection between metasomatism - the change in chemical composition of a rock via interaction with a fluid or melt - and the formation of metalliferous ore deposits in the Earth’s crust is well established. Similarly, it is now accepted that the Earth’s lithospheric mantle has experienced...